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Retroviral RLI/4-1 BBL and RLI/FLT3L Combination Immunomodulatory Gene Therapy for Glioblastoma

Retroviral RLI/4-1 BBL and RLI/FLT3L Combination Immunomodulatory Gene Therapy for Glioblastoma
逆转录病毒 RLI/4-1 BBL 和 RLI/FLT3L 联合免疫调节基因治疗胶质母细胞瘤
批准号：
10740288
负责人：
Manish Aghi
金额：
$9.5万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
项目状态：
已结题
起止时间：
2023-02-15 至 2023-12-31
来源：
https://reporter.nih.gov/project-details/10740288
关键词：
AwardFLT3 ligandGlioblastomaParentsResearchcareergene therapyimmunoregulationparent grant

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英文摘要
PROJECT SUMMARY/ABSTRACT This proposed project is within the scope of R01NS123808. There are no changes to the Project Summary/Narrative of the Parent Award. A brief description of the Parent Grant Specific Aims is provided within the Research and Career Plan.
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Retroviral RLI immunomodulatory gene therapy for glioblastoma
Modeling and druggable-genome screening of glioblastoma invasion using regional biopsy-guided biomaterials systems
Modeling and druggable-genome screening of glioblastoma invasion using regional biopsy-guided biomaterials systems
Tumor cell and microenvironment changes causing antiangiogenic therapy resistance
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