Clinical and Translational Research Innovation in Dental Schools (ClinTrain-RIDeS)

牙科学校的临床和转化研究创新 (ClinTrain-RIDeS)

• 批准号: 10754747
• 负责人: Lisa Berens
• 金额: $ 80.47万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-13 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10754747
• 关键词: 3-Dimensional; Adherence; Adult; Alaska; Apical; Applications Grants; Area; Artificial Intelligence; Basic Science; California; Clinic; Clinical; Clinical Practice Guideline; Clinical Research; Clinical Research Protocols; Clinical Sciences; Collaborations; Communities; Community Dentistry; Consent; Data; Data Analyses; Data Collection; Decision Making; Dental; Dental Care; Dental Education; Dental Faculty; Dental Research; Dental Schools; Dental Students; Dental caries; Dentistry; Dentists; Detection; Development; Diagnosis; Diagnostic; Discipline; Education; Educational Curriculum; Environment; Evidence based practice; Evidence based treatment; Faculty; Feasibility Studies; Fostering; Funding; Future; Goals; Health system; In Situ; Incubated; Incubators; Individual; Industry; Infrastructure; Institution; Lead; Learning; Medicine; Mentors; Mentorship; Methods; Mission; Modality; National Institute of Dental and Craniofacial Research; Nursing Faculty; Oral Examination; Oral health; Patient Care; Patients; Periodicals; Phase; Pilot Projects; Postdoctoral Fellow; Practice Guidelines; Practice based research; Process; Professional Education; Prognosis; Program Development; Prospective, cohort study; Protocols documentation; Recording of previous events; Research; Research Activity; Research Design; Research Methodology; Research Personnel; Research Project Grants; Research Training; Resources; Roentgen Rays; Scanning; School Dentistry; Schools; Scientist; Silicon; Site; Specialist; Students; Testing; Time; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; Visit; accurate diagnosis; artificial intelligence algorithm; base; clinical decision support; clinical practice; clinically relevant; college; cost; design; doctoral student; education research; evidence base; experience; externship; faculty community; faculty research; improved; industry partner; innovation; member; novel diagnostics; peer coaching; population health; pre-doctoral; programs; prospective; recruit; research faculty; research study; skill acquisition; skills; student mentoring; support tools; supportive environment; treatment guidelines; treatment planning; usability

Abstract The overall goal of UCSF’s Clinical and Translational Research Innovation in Dental School (ClinTrain-RIDeS) is to develop future dentist-scientists and establish a clinical research enterprise at the UCSF School of Dentistry and Northern California through the following aims: 1) Provide clinical research training and skills development to UCSF Dentistry’s community of clinicians (predoctoral students, postgraduate residents, faculty) and to other collaborating partners – UCSF Dentistry- affiliated clinical faculty from Community-Based Clinical Education externship sites in California and Alaska and clinical faculty at California Northstate University College of Dental Medicine. The successful training programs and courses from the UCSF Clinical and Translational Sciences Institute (CTSI) will be adapted and tailored for School of Dentistry residents and faculty, and dental research faculty will facilitate small group sessions to provide mentoring on developing a clinical research protocol. For predoctoral students, the existing research methods curriculum required of all dental students will be redesigned to expand clinical research topics and a new quality improvement course will be developed. Dental students will also be supported to participate in CTSI’s Yearlong Inquiry Program and obtain a certificate/master’s in clinical research degree. 2) Develop a Practice-based Clinical Research Incubator Program at the UCSF Dental Center to foster conducting clinical research studies by building and expanding on effective mentorship and sponsorship initiatives at UCSF and in the School of Dentistry. Mentoring will be available to trainees in all phases of designing and implementing their clinical research including forming project ideas, developing them into protocols, applying for intramural funds, implementing research, and disseminating findings. 3) Conduct small-scale practice-based clinical research projects prospectively collecting data, starting with (a) validating the accuracy and adherence to evidence-based treatment guidelines of artificial intelligence (AI)- generated caries diagnoses and treatment plans compared to faculty-approved student-dentist diagnoses and treatment plans with assistance from UCSF’s APeX-Enabled Research Program and leading industry partners (Retrace.ai); and (b) assessing the usability of a real-time dental AI clinical decision support tool among predoctoral student-dentists and clinical faculty. Future small-scale research projects will be clinical faculty- generated and prioritized based on observations from their daily clinical practices. Together these aims will catalyze UCSF to be a leader in practice-based clinical research in Northern California dental schools, which have a diverse patient base permitting favorable generalizability and applicability of findings.

摘要 加州大学旧金山分校牙科院校临床与转化性研究创新的总体目标 是培养未来的牙医科学家，并在加州大学旧金山分校建立临床研究企业 牙科和北加州通过以下目标： 1)为加州大学旧金山分校牙科社区的临床医生提供临床研究培训和技能发展 (博士后学生、研究生住院医生、教师)和其他合作伙伴-加州大学旧金山分校牙科- 来自加利福尼亚州和阿拉斯加社区临床教育外部实习地点的附属临床教师 以及加州西北州立大学牙科医学院的临床教员。成功的培训 加州大学旧金山分校临床和翻译科学研究所(CTSI)的计划和课程将被调整和 为口腔医学院住院医生和教职员工量身定做，牙科研究教职员工将为小组提供便利 会议提供关于制定临床研究方案的指导。对于博士前学生，现有的 所有牙科学生必修的研究方法课程将重新设计，以扩大临床研究 主题和一个新的质量改进课程将被开发。牙科学生也将得到支持，以 参加CTSI为期一年的研究项目，并获得临床研究学位证书/硕士学位。 2)在加州大学旧金山分校牙科中心开发以实践为基础的临床研究孵化器计划，以促进 通过建立和扩大有效的指导和赞助来进行临床研究 加州大学旧金山分校和牙科学院的倡议。将为学员提供以下各个阶段的指导 设计和实施他们的临床研究，包括形成项目想法，将其发展为 方案、申请内部资金、实施研究和传播研究成果。 3)开展以实践为基础的小规模临床研究项目，前瞻性地收集数据，从 (A)验证人工智能(AI)循证治疗指南的准确性和遵守情况- 生成的龋齿诊断和治疗计划与教师批准的学生牙医诊断和治疗计划进行比较 由加州大学旧金山分校的顶尖支持研究计划和领先的行业合作伙伴提供帮助的治疗计划 (Retrace.ai)；和(B)评估实时牙科人工智能临床决策支持工具的可用性 博士前学生-牙医和临床教师。未来的小规模研究项目将是临床教员- 根据他们日常临床实践中的观察结果生成并确定优先顺序。这些目标加在一起将 催化加州大学旧金山分校成为北加州牙科学校以实践为基础的临床研究的领导者， 拥有多样化的患者基础，从而使研究结果具有良好的概括性和适用性。