Clinical and Translational Research Innovation in Dental Schools (ClinTrain-RIDeS)

牙科学校的临床和转化研究创新 (ClinTrain-RIDeS)

• 批准号: 10754747
• 负责人: Lisa Berens
• 金额: $ 80.47万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-13 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10754747
• 关键词: 3-Dimensional; Adherence; Adult; Alaska; Apical; Applications Grants; Area; Artificial Intelligence; Basic Science; California; Clinic; Clinical; Clinical Practice Guideline; Clinical Research; Clinical Research Protocols; Clinical Sciences; Collaborations; Communities; Community Dentistry; Consent; Data; Data Analyses; Data Collection; Decision Making; Dental; Dental Care; Dental Education; Dental Faculty; Dental Research; Dental Schools; Dental Students; Dental caries; Dentistry; Dentists; Detection; Development; Diagnosis; Diagnostic; Discipline; Education; Educational Curriculum; Environment; Evidence based practice; Evidence based treatment; Faculty; Feasibility Studies; Fostering; Funding; Future; Goals; Health system; In Situ; Incubated; Incubators; Individual; Industry; Infrastructure; Institution; Lead; Learning; Medicine; Mentors; Mentorship; Methods; Mission; Modality; National Institute of Dental and Craniofacial Research; Nursing Faculty; Oral Examination; Oral health; Patient Care; Patients; Periodicals; Phase; Pilot Projects; Postdoctoral Fellow; Practice Guidelines; Practice based research; Process; Professional Education; Prognosis; Program Development; Prospective, cohort study; Protocols documentation; Recording of previous events; Research; Research Activity; Research Design; Research Methodology; Research Personnel; Research Project Grants; Research Training; Resources; Roentgen Rays; Scanning; School Dentistry; Schools; Scientist; Silicon; Site; Specialist; Students; Testing; Time; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; Visit; accurate diagnosis; artificial intelligence algorithm; base; clinical decision support; clinical practice; clinically relevant; college; cost; design; doctoral student; education research; evidence base; experience; externship; faculty community; faculty research; improved; industry partner; innovation; member; novel diagnostics; peer coaching; population health; pre-doctoral; programs; prospective; recruit; research faculty; research study; skill acquisition; skills; student mentoring; support tools; supportive environment; treatment guidelines; treatment planning; usability

Abstract The overall goal of UCSF’s Clinical and Translational Research Innovation in Dental School (ClinTrain-RIDeS) is to develop future dentist-scientists and establish a clinical research enterprise at the UCSF School of Dentistry and Northern California through the following aims: 1) Provide clinical research training and skills development to UCSF Dentistry’s community of clinicians (predoctoral students, postgraduate residents, faculty) and to other collaborating partners – UCSF Dentistry- affiliated clinical faculty from Community-Based Clinical Education externship sites in California and Alaska and clinical faculty at California Northstate University College of Dental Medicine. The successful training programs and courses from the UCSF Clinical and Translational Sciences Institute (CTSI) will be adapted and tailored for School of Dentistry residents and faculty, and dental research faculty will facilitate small group sessions to provide mentoring on developing a clinical research protocol. For predoctoral students, the existing research methods curriculum required of all dental students will be redesigned to expand clinical research topics and a new quality improvement course will be developed. Dental students will also be supported to participate in CTSI’s Yearlong Inquiry Program and obtain a certificate/master’s in clinical research degree. 2) Develop a Practice-based Clinical Research Incubator Program at the UCSF Dental Center to foster conducting clinical research studies by building and expanding on effective mentorship and sponsorship initiatives at UCSF and in the School of Dentistry. Mentoring will be available to trainees in all phases of designing and implementing their clinical research including forming project ideas, developing them into protocols, applying for intramural funds, implementing research, and disseminating findings. 3) Conduct small-scale practice-based clinical research projects prospectively collecting data, starting with (a) validating the accuracy and adherence to evidence-based treatment guidelines of artificial intelligence (AI)- generated caries diagnoses and treatment plans compared to faculty-approved student-dentist diagnoses and treatment plans with assistance from UCSF’s APeX-Enabled Research Program and leading industry partners (Retrace.ai); and (b) assessing the usability of a real-time dental AI clinical decision support tool among predoctoral student-dentists and clinical faculty. Future small-scale research projects will be clinical faculty- generated and prioritized based on observations from their daily clinical practices. Together these aims will catalyze UCSF to be a leader in practice-based clinical research in Northern California dental schools, which have a diverse patient base permitting favorable generalizability and applicability of findings.

抽象的 加州大学旧金山分校牙科学院临床和转化研究创新（ClinTrain-RIDeS）的总体目标 旨在培养未来的牙医科学家并在加州大学旧金山分校医学院建立临床研究企业 牙科和北加州通过以下目标： 1) 为 UCSF 牙科临床医生社区提供临床研究培训和技能发展 （博士生、研究生、教师）以及其他合作伙伴 – 加州大学旧金山分校牙科学院 – 来自加利福尼亚州和阿拉斯加社区临床教育实习基地的附属临床教师 以及加州北州立大学牙科医学院的临床教师。此次培训取得圆满成功 加州大学旧金山分校临床和转化科学研究所 (CTSI) 的项目和课程将进行调整并 为牙科学院住院医师和教职人员量身定制，牙科研究教职人员将促进小组活动 会议为制定临床研究方案提供指导。对于博士前学生来说，现有的 所有牙科学生所需的研究方法课程将重新设计，以扩大临床研究 将开发主题和新的质量改进课程。牙科学生也将获得支持 参加 CTSI 的年度探究计划并获得临床研究学位证书/硕士学位。 2) 在 UCSF 牙科中心制定基于实践的临床研究孵化器计划，以培养 通过建立和扩展有效的指导和赞助来进行临床研究 加州大学旧金山分校和牙科学院的倡议。将为各个阶段的学员提供指导 设计和实施他们的临床研究，包括形成项目想法，将其发展为 协议、申请校内资金、实施研究和传播研究结果。 3) 开展小规模基于实践的临床研究项目，前瞻性地收集数据，首先 (a) 验证人工智能 (AI) 循证治疗指南的准确性和遵守情况 - 与教师批准的学生牙医诊断进行比较，生成龋齿诊断和治疗计划， 在 UCSF 的 APeX-Enabled 研究计划和领先行业合作伙伴的协助下制定治疗计划 （Retrace.ai）； (b) 评估实时牙科人工智能临床决策支持工具的可用性 博士前学生牙医和临床教师。未来的小规模研究项目将是临床教师- 根据日常临床实践的观察结果生成并确定优先级。这些目标共同将 促进 UCSF 成为北加州牙科学校基于实践的临床研究的领导者， 拥有多样化的患者基础，使得研究结果具有良好的普遍性和适用性。