Clinical and Translational Research Innovation in Dental Schools (ClinTrain-RIDeS)

摘要 加州大学旧金山分校牙科学院临床和转化研究创新（ClinTrain-RIDeS）的总体目标 是培养未来的牙医科学家，并建立一个临床研究企业在加州大学旧金山分校的学校， 牙科和北方加州通过以下目标： 1)为UCSF牙科的临床医生社区提供临床研究培训和技能发展 （博士前学生，研究生居民，教师）和其他合作伙伴- UCSF牙科- 来自加州和阿拉斯加社区临床教育实习基地的附属临床教师 和临床教员在加州北州大学牙科医学院。成功的训练 来自UCSF临床和转化科学研究所（CTSI）的课程和课程将被改编， 为牙科居民和教师量身定制的学校，牙科研究教师将促进小组 会议提供指导，制定临床研究方案。对于博士生，现有的 将重新设计所有牙科学生所需的研究方法课程，以扩大临床研究 将制定专题和新的质量改进课程。牙科学生也将得到支持， 参加CTSI的为期一年的调查计划，并获得临床研究学位证书/硕士学位。 2)在UCSF牙科中心开发基于实践的临床研究孵化器计划，以促进 通过建立和扩大有效的指导和赞助来开展临床研究 在加州大学旧金山分校和牙科学院的倡议。将在培训的所有阶段向学员提供指导， 设计和实施他们的临床研究，包括形成项目想法，将其发展为 协议，申请校内资金，实施研究，并传播研究结果。 3)进行小规模的基于实践的临床研究项目，前瞻性地收集数据，从 (a)验证人工智能（AI）循证治疗指南的准确性和依从性- 生成的龋齿诊断和治疗计划相比，学院批准的学生牙医诊断， 在UCSF的ApeX启用研究计划和领先的行业合作伙伴的帮助下， （Retrace.ai）;以及（B）评估实时牙科AI临床决策支持工具在 博士前学生牙医和临床教师。未来的小规模研究项目将是临床教师- 根据他们日常临床实践的观察结果生成并优先排序。这些目标将 促进UCSF成为北方加州牙科学校基于实践的临床研究的领导者， 有一个多样化的病人基础，允许有利的普遍性和适用性的发现。

Abstract The overall goal of UCSF’s Clinical and Translational Research Innovation in Dental School (ClinTrain-RIDeS) is to develop future dentist-scientists and establish a clinical research enterprise at the UCSF School of Dentistry and Northern California through the following aims: 1) Provide clinical research training and skills development to UCSF Dentistry’s community of clinicians (predoctoral students, postgraduate residents, faculty) and to other collaborating partners – UCSF Dentistry- affiliated clinical faculty from Community-Based Clinical Education externship sites in California and Alaska and clinical faculty at California Northstate University College of Dental Medicine. The successful training programs and courses from the UCSF Clinical and Translational Sciences Institute (CTSI) will be adapted and tailored for School of Dentistry residents and faculty, and dental research faculty will facilitate small group sessions to provide mentoring on developing a clinical research protocol. For predoctoral students, the existing research methods curriculum required of all dental students will be redesigned to expand clinical research topics and a new quality improvement course will be developed. Dental students will also be supported to participate in CTSI’s Yearlong Inquiry Program and obtain a certificate/master’s in clinical research degree. 2) Develop a Practice-based Clinical Research Incubator Program at the UCSF Dental Center to foster conducting clinical research studies by building and expanding on effective mentorship and sponsorship initiatives at UCSF and in the School of Dentistry. Mentoring will be available to trainees in all phases of designing and implementing their clinical research including forming project ideas, developing them into protocols, applying for intramural funds, implementing research, and disseminating findings. 3) Conduct small-scale practice-based clinical research projects prospectively collecting data, starting with (a) validating the accuracy and adherence to evidence-based treatment guidelines of artificial intelligence (AI)- generated caries diagnoses and treatment plans compared to faculty-approved student-dentist diagnoses and treatment plans with assistance from UCSF’s APeX-Enabled Research Program and leading industry partners (Retrace.ai); and (b) assessing the usability of a real-time dental AI clinical decision support tool among predoctoral student-dentists and clinical faculty. Future small-scale research projects will be clinical faculty- generated and prioritized based on observations from their daily clinical practices. Together these aims will catalyze UCSF to be a leader in practice-based clinical research in Northern California dental schools, which have a diverse patient base permitting favorable generalizability and applicability of findings.