Leveraging Community-Academic Partnerships and Social Networks to Disseminate Vaccine-Related Information and Increase Vaccine Uptake Among Black Individuals with Rheumatic Diseases

项目总结 包括关节炎在内的慢性风湿病患者约占美国人口的25%。 人口。种族/族裔和社会经济差距在不利的、往往可以避免的结果中几乎发生 所有风湿病，特别是在黑人和社会经济地位较低的人中。尽管 风湿病患者接种疫苗的重要性，以及严重感染率高， 疫苗接种率一直很低。在美国，新冠肺炎疫苗接种率较低，疫苗接种迟疑不决 黑人患者比白人患者更高，风湿性疾病也是如此。与 新冠肺炎大流行揭示的深刻差异因风湿性疾病已证实的差异而加剧 疾病结果，以及对感染的易感性增加，迫切需要解决疫苗不足的问题 患有这些疾病的黑人个体的吸收和犹豫。此外，还必须增加 免疫受抑的风湿病患者社会网络中的疫苗接种率 并且可能没有那么强健的疫苗接种反应。我们的团队打造了长期的社区学术 波士顿和芝加哥地区的合作伙伴关系，以了解患有狼疮的黑人患者的需求 系统性风湿病，以及种族主义在卫生和医疗保健方面发挥的作用。被公众陷害 健康关键种族实践承认种族主义在我们社会中的普遍存在，我们将利用我们的 社区-学术合作伙伴关系，以实施疾控中心的民意领袖(POL)模式 受信任的社区领导人接受培训，通过以下途径传播有关新冠肺炎疫苗的信息 他们在以黑人为主的社区中的社交网络，以增加疫苗接种率，减少犹豫。在……里面 对NOSI NOT-MD-21-008的响应：解决疫苗迟疑、吸收和实施问题的研究 在经历差异的人群中，我们提出了以下目标：目标1.利用社区- 在美国两个城市建立学术合作伙伴关系，为POL开发培训和评估材料。目标2a。至 在有和没有种族正义框架的情况下建立以社区为基础的干预的有效性，以提高 新冠肺炎疫苗的接受和减少风湿黑人个体社会网络中的犹豫 条件。我们将进行一项整群随机对照试验，以测试Pols是否接受了种族正义培训 嵌入疫苗安全性和有效性信息的框架将导致更多人接种新冠肺炎疫苗 在他们的社交网络成员中，比较单独的安全和功效培训。目标2b。要确定 波兰人外展社会网络的结构和组成。我们将改进现有的POL模式 通过添加一种经过验证的混合方法来比较每个手臂上的POL所达到的社交网络。 我们假设，加入种族正义镜头将使警察能够传播更多信息 更广泛和更有说服力，并通过减少恐惧和不信任来增加疫苗接种量。

PROJECT SUMMARY Individuals with chronic rheumatic diseases including arthritis comprise approximately 25% of the U.S. population. Racial/ethnic and socioeconomic disparities in adverse, often avoidable outcomes occur in nearly all rheumatic diseases particularly among Black and lower socioeconomic status individuals. Despite the importance of vaccinations in patients with rheumatic diseases, and the high rates of serious infections, vaccine uptake is consistently poor. In the U.S., COVID-19 vaccine uptake is lower and vaccine hesitancy higher among Black patients compared with White patients, and this holds true in rheumatic diseases. With the profound disparities uncovered by the COVID-19 pandemic aggravated by proven disparities in rheumatic disease outcomes, and heightened vulnerability to infections, there is an urgent need to address low vaccine uptake and hesitancy among Black individuals with these conditions. In addition, it is critical to also increase vaccine uptake among the social networks of individuals with rheumatic diseases who are immunosuppressed and may have less robust vaccination responses. Our team has forged longstanding community-academic partnerships in the Boston and Chicago areas to understand the needs of Black individuals with lupus, a systemic rheumatic disease, and the role racism plays in health and healthcare access. Framed by the Public Health Critical Race Praxis that recognizes the pervasiveness of racism in our society, we will leverage our community-academic partnerships to implement the CDC's Popular Opinion Leader (POL) model whereby trusted community leaders are trained to disseminate information regarding COVID-19 vaccination through their social networks in predominately Black communities to increase vaccine uptake and reduce hesitancy. In response to the NOSI NOT-MD-21-008: Research to Address Vaccine Hesitancy, Uptake and Implementation among Populations that Experience Disparities, we propose the following aims: Aim 1. To leverage community- academic partnerships across two U.S. cities to develop training and evaluation materials for POLs. Aim 2a. To establish the efficacy of a community-based intervention with and without a racial justice framework to increase COVID-19 vaccine uptake and reduce hesitancy among social networks of Black individuals with rheumatic conditions. We will conduct a cluster randomized controlled trial to test whether POLs trained with racial justice framing embedded in information on vaccine safety and efficacy will result in greater COVID-19 vaccine uptake among their social network members compared to safety and efficacy training alone. Aim 2b. To determine the structure and composition of the outreach social networks of POLs. We will enhance the existing POL model by adding a validated mixed methods approach to compare the social networks reached by POLs in each arm. We hypothesize that incorporating a racial justice lens will empower POLs to disseminate information more broadly and more persuasively and increase vaccine uptake by reducing fear and mistrust.