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Project Summary/Abstract The University of Minnesota Medical School is committed to the recruitment, enrollment, research instruction, and mentoring of a diverse group of high-quality medical students with aspirations of a career in academic medicine. Based on surveys of medical students, as well as on an analysis by a faculty-driven Medical Student Research Task Force, we identified research training in the summer between years 1 and 2 as the critical opportunity to capture the interests and talents of academically minded medical students. Thus, this T35 competitive renewal application for a “Medical Student Summer Research Program in Infection and Immunity” represents our plan to continue to provide high quality medical student research instruction and mentorship. Our long-term objective is to significantly increase the number and diversity of medical students that obtain paid employment in medical research, that publish during medical school, and that eventually enter into physician-scientist training pathway residency programs. To this end, we describe herein our activities during the first 5 years of the program (including years 1-4 of this funded T35 grant) and offer the results of our current efforts based on the performance and perceptions of 30 medical student summer researchers. Daniel Mueller, MD, initially developed this Medical Student Summer Research Program in Infection and Immunity, and will continue to lead this T35 training grant. He has a breadth of experience in academic medicine including a) laboratory-based research that includes both fundamental and human-oriented investigation into autoimmune disease pathogenesis, b) medical leadership as a division director, c) an extensive undergraduate and pre-doctoral training record, and d) direct patient care in Rheumatology. Mueller will be assisted by numerous Medical School leaders with records of success in research and mentorship, and will receive additional financial support from the Chair of Medicine and the Dean of the Medical School. A total of 31 outstanding Center for Immunology faculty members will serve as the preceptors for 7 summer medical students in each year of the grant period. Diverse student candidates will be approached by the T35 director on an individual basis, and encouraged to apply to the program. Students entering the program will receive direct instruction in scientific investigation for a period of 2 months. Students will also receive weekly instruction that relates the function of the immune system to human health. Training experiences will include the writing of a formal “Specific Aims Page” proposal, as well as a “Progress Report” final summary of their research. In addition, fellows will prepare and present to Center for Immunology faculty both a scientific poster and oral presentation of their work. Finally, trainees will be given the opportunity for longitudinal mentorship regarding the physician-scientist career path throughout their medical school experience. Success in this program will be monitored both through longitudinal surveys of students and training faculty as well as through oversight by both Internal and External Advisors.
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DOI: 10.1093/ofid/ofaa602
发表时间: 2021-03
期刊: Open forum infectious diseases
影响因子: 4.2
作者: [Pullen MF, Pastick KA, Williams DA, Nascene AA, Bangdiwala AS, Okafor EC, Hullsiek KH, Skipper CP, Lofgren SM, Engen N, Abassi M, McDonald EG, Lee TC, Rajasingham R, Boulware DR]
通讯作者: Boulware DR
DOI: 10.1016/j.celrep.2019.07.059
发表时间: 2019-08-20
期刊: Cell reports
影响因子: 8.8
作者: [Burrack AL, Spartz EJ, Raynor JF, Wang I, Olson M, Stromnes IM]
通讯作者: Stromnes IM
DOI: 10.3389/fimmu.2018.02532
发表时间: 2018
期刊: Frontiers in immunology
影响因子: 7.3
作者: [Sjaastad FV, Condotta SA, Kotov JA, Pape KA, Dail C, Danahy DB, Kucaba TA, Tygrett LT, Murphy KA, Cabrera-Perez J, Waldschmidt TJ, Badovinac VP, Griffith TS]
通讯作者: Griffith TS
Differential hydrogen sulfide production by a human cohort in response to animal- and plant-based diet interventions.
人类群体响应基于动物和植物的饮食干预而产生的硫化氢差异。
DOI: 10.1016/j.clnu.2022.03.028
发表时间: 2022
期刊: Clinical nutrition (Edinburgh, Scotland)
影响因子: --
作者: [Teigen,Levi, Mathai,PrinceP, Lopez,Sharon, Matson,Michael, Elkin,Baila, Kozysa,Daria, Kabage,AmandaJ, Hamilton,Matthew, Vaughn,ByronP, Sadowsky,MichaelJ, Khoruts,Alexander]
通讯作者: Khoruts,Alexander
6
    Medical Student Summer Research Program in Infection and Immunity
    • 批准号:
      9097536
    • 项目类别:
    • 资助金额:
      $2.98万
    • 财政年份:
      2015
    • 负责人:
      Daniel L Mueller
    • 依托单位:
    Functional characterization of anergic helper T cells
    • 批准号:
      8308580
    • 项目类别:
    • 资助金额:
      $35.22万
    • 财政年份:
      2011
    • 负责人:
      Daniel L Mueller
    • 依托单位:
    Epigenetic Control of T cell Autoimmunity
    • 批准号:
      7914393
    • 项目类别:
    • 资助金额:
      $37.75万
    • 财政年份:
      2009
    • 负责人:
      Daniel L Mueller
    • 依托单位:
    Epigenetic Control of T cell Autoimmunity
    • 批准号:
      7727443
    • 项目类别:
    • 资助金额:
      $37.75万
    • 财政年份:
      2009
    • 负责人:
      Daniel L Mueller
    • 依托单位:
    国内基金
    海外基金
    Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis