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中文摘要
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核心A:行政项目总结 该核心为所有其他组件提供协调和集成,并确保研究 并实现了中心的方案目标。行政领导由《纲领》组成 总干事、两名副主任和执行主任。他们得到了领导委员会的协助 这包括这些个人、各组成部分的领导人和其他高级教职员工。管理核心 支持、监测和协调亚洲发展研究中心所有组成部分的活动。 1.建立和维持行政结构和治理,包括预算监督,未来 规划和优化资源利用,以实现中心的总体目标。 2.协调和整合发展与和解委员会的所有活动和组成部分,用于研究、培训、信息和 与内部和外部的独立调查人员进行生物菌素转移和资源共享 华盛顿大学(吴)。 3.促进科学和教育互动(包括公共关系)和关于阿尔茨海默氏症的合作 所有级别的疾病(AD)和相关痴呆(ADRD)(重点是初级调查人员)与其他 吴教授,其他阿尔茨海默病中心,国家老龄研究所(NIA),阿尔茨海默氏症 协会(地方和国家),以及大圣路易斯地区的专业和非专业社区。 4.征集、评估、选择和监督开发性项目。 5.规定Knight ADRC的外部咨询委员会定期进行外部审查,并实现 内部审查。 6.确保遵守人类受试者研究、动物福利、科学研究的所有法规要求 诚信、数据和样本共享、公共获取政策和金融政策要求 国立卫生研究院(NIH)。CORE A还将监测并定期评估其他骑士ADRC 各组成部分对国家适应行动方案的目标作出反应。
英文摘要
Core A: Administration Project Summary This Core provides coordination and integration for all other Components and acts to insure that the research and programmatic goals of the Center are met. The administrative leadership consists of the Program Director, two Associate Directors, and the Executive Director. They are assisted by the Leadership Committee that includes these individuals, leaders of the Components and other senior faculty. The Administration Core supports, monitors and coordinates the activities of all components of the ADRC. 1. Establish and maintain administrative structure and governance, including budgetary oversight, future planning, and optimal resource utilization, to meet the overall goals of the Center. 2. Coordinate and integrate all ADRC activities and Components for research, training, information and biospecimen transfer and resource sharing with independent investigators both internal and external to Washington University (WU). 3. Promote scientific and educational interactions (including public relations) and collaborations on Alzheimer disease (AD) and related dementias (ADRD) at all levels (emphasizing junior investigators) with other faculty at WU, other Alzheimer Disease Centers, the National Institute on Aging (NIA), the Alzheimer's Association (locally and nationally), and the professional and lay communities of the greater St. Louis area. 4. Solicit, evaluate, select, and monitor the Developmental Projects. 5. Provide for periodic external review of the Knight ADRC by its External Advisory Committee and achieve internal review. 6. Ensure compliance with all regulatory requirements for human subjects research, animal welfare, scientific integrity, data and sample sharing, public access policies, and financial policy requirements of WU and the National Institutes of Health (NIH). Core A also will monitor and regularly assess how other Knight ADRC components are responsive to NAPA goals.
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Cerebral amyloid angiopathy: Role of ApoE, innate immunity, and meningeal lymphatics
  • 批准号:
    10674679
  • 项目类别:
  • 资助金额:
    $62.0万
  • 财政年份:
    2022
  • 负责人:
    DAVID M. HOLTZMAN
  • 依托单位:
APOE effects on glial lipid metabolism and 25-hydroxycholesterol: Effects on aging and AD-related pathology
  • 批准号:
    10667466
  • 项目类别:
  • 资助金额:
    $53.02万
  • 财政年份:
    2021
  • 负责人:
    DAVID M. HOLTZMAN
  • 依托单位:
APOE effects on glial lipid metabolism and 25-hydroxycholesterol: Effects on aging and AD-related pathology
  • 批准号:
    10407944
  • 项目类别:
  • 资助金额:
    $54.01万
  • 财政年份:
    2021
  • 负责人:
    DAVID M. HOLTZMAN
  • 依托单位:
Alzheimer's Disease Research Center
  • 批准号:
    10622633
  • 项目类别:
  • 资助金额:
    $307.63万
  • 财政年份:
    2020
  • 负责人:
    DAVID M. HOLTZMAN
  • 依托单位:
海外基金