Internal Sources of Minority Stress and Alcohol Consumption

少数群体压力和饮酒的内部根源

• 批准号: 10742318
• 负责人: Amelia E. Talley
• 金额: $ 39.79万
• 依托单位: TEXAS TECH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-02 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10742318
• 关键词: Adult; Alcohol abuse; Alcohol consumption; Alcoholic Beverages; Area; Baseline Surveys; Behavior; Belief; Beverages; Biology; Bisexual; Blood Pressure; Books; Communities; Consumption; Dependence; Development; Disparity; Distress; Drug abuse; Enrollment; Ethanol; Expectancy; Experimental Designs; Exposure to; Feeling; Female; Funding; Gays; Gender Identity; Goals; Health; Heart Rate; Heavy Drinking; Hormones; Hydrocortisone; Individual; Individual Differences; Intervention; Intoxication; Knowledge; Lesbian; Link; Measures; Methods; National Institute on Alcohol Abuse and Alcoholism; Participant; Persons; Physiological; Placebos; Positioning Attribute; Process; Psychological Stress; Randomized; Reaction; Reporting; Research; Risk; Role; Salivary; Scientist; Sex Differences; Sex Orientation; Sexuality; Shapes; Source; Speech; Stress; Taste Perception; Testing; Uncertainty; Underrepresented Populations; United States National Institutes of Health; Woman; Work; addiction; alcohol cue; alcohol effect; alcohol expectancy; alcohol research; alcohol response; alpha-amylase; biological adaptation to stress; biological sex; breath alcohol measurement; cisgender; clinically relevant; design; drinking; drinking behavior; emerging adult; experimental study; gender difference; health disparity; high risk; improved; interest; laboratory experiment; male; marginalized community; minority stress; minority stressor; movie; peer; pharmacologic; psychologic; psychological distress; recruit; response; sex; sexual identity; sexual minority community; sexual minority group; sexual role; social stigma; social stressor; stress reactivity; stressor; theories

7. Project Summary/Abstract Consistent with NIAAA’s expressed goal to understand sex differences in risk of problem alcohol use and target mechanisms that contribute to known disparities within high-risk communities, the current proposal seeks to examine the role of internal sources of minority stress (i.e., stress unique to those from marginalized communities) in potentiating heavy alcohol use, particularly among female and male bisexual/bi+ individuals. Prior work has focused almost exclusively on sources of minority stress among those who already identify as lesbian, gay, or bisexual. The proposed project seeks to examine physiological and psychological mechanisms that account for consumption among adults who report uncertainty about their sexual orientation, or sexual identity uncertainty (SIU). Uncertainty-identity theory suggests that when someone feels uncertain about a core aspect of their identity, they are motivated to reduce resulting psychological distress, which can account for increased alcohol consumption. No study, to date, has used an experimental design to examine physiological stress responses to ethanol consumption following exposure to internal sources of minority stress. The proposed work will test for differences in consumption and alleviation of distress based, in part, on participants’ physiological stress responses and the pharmacological effects of ethanol. This application proposes to recruit 200 cisgender participants with varying levels of SIU and uses a 3 x 2 x 5 mixed-factorial design. Participants will be randomly assigned to give one of three speeches, as part of an adapted Trier Social Stressor Test (TSST): (a) Relevant Proximal Stressor-TSST: development of their sexuality, including any feelings of uncertainty; (b) Irrelevant Proximal Stressor-TSST: development of their gender identity, including any feelings of uncertainty; or (c) Control-TSST: a recent book, movie, or TV show. Participants will then engage in a 35- minute ad libitum taste-test (ethanol, placebo). Project design includes: (a) a baseline survey and (b) experimental lab session that measures (i) alcohol consumption and 5 assessments of: (ii) breath alcohol concentration, (iii) salivary stress hormones, (iv) heart rate, (v) blood pressure, (vi) psychological distress, and (vii) perceived intoxication. Participants’ SIU and biological sex will alter the effect of condition on consumption. Indirect effects are expected, such that exposure to relevant internal sources of minority stress is expected to increase stress responses, which will account for drinking amount among those with higher SIU. We will also determine the extent to which physiological stress-dampening effects and perceived intoxication account for reductions in distress following drinking, depending on participant sex, whether beverages contain ethanol (or not), and positive beliefs about alcohol’s effects. Results will inform interventions that target physiological and psychological processes, especially those reinforcing use following exposure to internalized minority stressors.

7。项目摘要/摘要 与NIAAA的意识到的目标是了解性饮酒风险的性别差异和 目前的提案有助于高风险社区内已知分布的目标机制 试图检查少数族裔压力的内部来源的作用（即边缘化的压力所特有的压力 社区）潜在的大量饮酒，尤其是在女性和男性双性恋/BI+个人中。 先前的工作几乎专注于已经确定为 女同性恋，同性恋或双性恋。拟议的项目旨在检查生理和心理机制 这是报告对性取向不确定性或性行为的成年人的消费 身份不确定性（SIU）。不确定性认同理论表明，当某人对核心感到不确定时 他们身份的方面，他们有动力减少产生的心理困扰，这可以解释 饮酒量增加。迄今为止，还没有研究使用实验设计来检查生理 暴露于少数族裔压力的内部来源后，对乙醇消耗的压力反应。 拟议的工作将测试基于参与者的消费和缓解遇险的差异 生理压力反应和乙醇的药物作用。此申请提案要招募 200个具有不同SIU水平的Cisgender参与者，并使用3 x 2 x 5的混合因素设计。参与者 作为适应性的Trier社会压力测试的一部分，将随机分配以发表三种演讲之一 （TSST）：（a）相关的近端压力源-TSST：其性的发展，包括任何感受 不确定; （b）近端压力源-TSST：发展其性别认同，包括任何感觉 不确定性；或（c）Control-TSST：最近的书，电影或电视节目。然后，参与者将参与35- 分钟自发的味觉测试（乙醇，安慰剂）。项目设计包括：（a）基线调查和（b） 测量饮酒和5次评估的实验实验室会议：（ii）呼吸酒精 浓度，（iii）唾液应激角，（iv）心率，（v）血压，（vi）心理困扰和心理困扰和 （vii）感知中毒。参与者的SIU和生物学性别将改变状况对消费的影响。 期望间接影响，因此预计会暴露于相关的少数派压力的内部来源 增加压力反应，这将解释SIU较高的人的饮酒量。我们也会 确定身体压力阻尼的影响的程度，并认为 饮酒后的痛苦减少，具体取决于参与性别，饮料是否含有乙醇（或 不是），以及对酒精影响的积极信念。结果将为您的干预措施提供信息，以针对生理和 心理过程，特别是那些在暴露于内部少数派压力源后加强使用的过程。