TASK ORDER 01 COCAINE INTERACTION SAFETY STUDIES IN RATS. TOXICOLOGICAL EVALUATIONS OF POTENTIAL MEDICATIONS IDIQ. ORDERING PERIOD: 09/12/2023 - 09/11/2024. NIDA REF. NO. N01DA-23-8939

任务单 01 可卡因相互作用在大鼠中的安全性研究。

• 批准号: 10947939
• 负责人: Maria Arolfo
• 金额: $ 57.12万
• 依托单位: SRI INTERNATIONAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-12 至 2024-09-11
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10947939
• 关键词: Cocaine; Evaluation; National Institute of Drug Abuse; Pharmaceutical Preparations; Rattus; Toxicology; safety study

The overall objective of this contract is to provide NIDA with safety pharmacology & toxicology testing services for novel compounds being developed for the treatment of substance use disorders. SRI will perform pharmacology, safety, & toxicity studies to support Investigational New Drug and New Drug Application submissions to the U.S. FDA on compounds identified by the NIDA COR for inclusion in this program. The exact details of the work to be conducted for individual compounds or tasks will be determined on a case-by-case basis, as directed by the NIDA COR.

该合同的总体目标是为NIDA提供正在开发的用于治疗物质使用障碍的新型化合物的安全药理学和毒理学测试服务。SRI将进行药理学、安全性和毒性研究，以支持向美国FDA提交NIDA COR确定的化合物的研究性新药和新药申请，以纳入本计划。根据NIDA COR的指示，将根据具体情况确定针对单个化合物或任务进行的工作的确切细节。