Age of exposure and immunity to malaria in infants

点击翻译按钮获取中文摘要

The Perth group will investigate the influence of host genetics factors in the acquisition of malaria immunity in early life. Given that host genetic factors are likely to affect outcomes in all components of the study; these data should prove highly valuable to all collaborators. Objectives: To examine systematically a comprehensive range of host genetic factors relevant to the acquisition of naturally acquired immunity to malaria in small children and to analyse host genetic polymorphisms associated with favourable intermediate or clinical outcomes with respect to the timing of exposure to malarial parasites.