Administrative Core

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ADMINISTRATIVE CORE PROJECT SUMMARY The Administrative Core for the Vanderbilt Antibody and Antigen Discovery for Clostridioides difficile Vaccines (VANDy-CdV) program will serve to integrate and facilitate the broad range of activities that will be undertaken within the program. This core will benefit from considerable administrative leadership experience among the team members as well as strong institutional support. Four specific aims/responsibilities are proposed. The first aim will be to coordinate program activities. The success of VANDy-CdV will depend on frequent and meaningful interactions between all investigators. A Local Steering Committee composed of project leaders, core directors, and key personnel will meet monthly to monitor progress, guide scientific directions, and to monitor finance- and compliance-related issues. In addition, a full team meeting will occur quarterly to foster productive and collaborative research. All VANDy-CdV members will be invited to share progress and solicit constructive feedback. The Administrative Core will plan, coordinate, and document the activities from these meetings. The second aim will be to interface with NIAID Program Officers and ensure that NIH reporting requirements are met. In addition to official reporting requirements, the Administrative Core will notify the NIH of all VANDy-CdV monthly and quarterly meetings. The Core will generate reports following each meeting and distribute these reports to Local Steering Committee leaders and NIAID Program Officers. The Administrative Core will also coordinate travel for VANDy-CdV members to attend and participate in Annual Programmatic Meetings. The third aim is to provide fiscal oversight. Vanderbilt University Medical Center is ultimately responsible for all spending decisions involving VANDy-CdV; however, the initial level of fiscal oversight will be the responsibility of the Administrative Core. The fourth aim is to manage intellectual property, resource and reagent distribution, and transmittal of data to public databases. Opportunities relating to intellectual property across the projects and cores will be handled by the Administrative Core in conjunction with the Vanderbilt Center for Commercialization and Technology Transfer (CTTC). The Administrative Core also will ensure that all reasonable requests for reagents from any VANDy-CdV program are satisfied within a timely manner.