Administrative Core

行政核心项目总结 艰难梭状芽胞杆菌Vanderbilt抗体和抗原发现的管理核心 疫苗(Vandy-CDV)计划将有助于整合和促进将是 在该计划内进行。这一核心将受益于相当多的行政领导经验。 团队成员之间以及强有力的机构支持。四个具体目标/责任是 建议。第一个目标将是协调计划活动。Vandy-CDV的成功将取决于 所有调查人员之间频繁而有意义的互动。由项目组成的地方指导委员会 领导、核心负责人和关键人员将每月开会，监测进展，指导科学方向，并 监督与财务和合规相关的问题。此外，每季度将召开一次完整的团队会议，以促进 富有成效和协作的研究。所有Vandy-CDV成员将被邀请分享进展并征集 建设性的反馈。行政核心将计划、协调和记录这些活动 开会。第二个目标将是与NIAID项目官员联系，并确保NIH报告 符合要求。除了官方的报告要求外，行政核心将通知NIH 所有范迪-CDV的月度和季度会议。核心小组将在每次会议后生成报告，并 将这些报告分发给地方指导委员会领导人和NIAID项目官员。行政部门 CORE还将协调范迪-CDV成员出席和参与年度计划的差旅 开会。第三个目标是提供财政监督。范德比尔特大学医学中心最终 负责涉及Vandy-CDV的所有支出决定；然而，最初的财政监督水平将是 行政核心的责任。第四个目标是管理知识产权、资源和 试剂分配，并将数据传输到公共数据库。与知识产权有关的机会 所有项目和核心将由行政核心与范德比尔特中心共同处理 用于商业化和技术转让(CTTC)。行政核心还将确保所有 任何范迪-CDV项目对试剂的合理要求都能及时得到满足。

ADMINISTRATIVE CORE PROJECT SUMMARY The Administrative Core for the Vanderbilt Antibody and Antigen Discovery for Clostridioides difficile Vaccines (VANDy-CdV) program will serve to integrate and facilitate the broad range of activities that will be undertaken within the program. This core will benefit from considerable administrative leadership experience among the team members as well as strong institutional support. Four specific aims/responsibilities are proposed. The first aim will be to coordinate program activities. The success of VANDy-CdV will depend on frequent and meaningful interactions between all investigators. A Local Steering Committee composed of project leaders, core directors, and key personnel will meet monthly to monitor progress, guide scientific directions, and to monitor finance- and compliance-related issues. In addition, a full team meeting will occur quarterly to foster productive and collaborative research. All VANDy-CdV members will be invited to share progress and solicit constructive feedback. The Administrative Core will plan, coordinate, and document the activities from these meetings. The second aim will be to interface with NIAID Program Officers and ensure that NIH reporting requirements are met. In addition to official reporting requirements, the Administrative Core will notify the NIH of all VANDy-CdV monthly and quarterly meetings. The Core will generate reports following each meeting and distribute these reports to Local Steering Committee leaders and NIAID Program Officers. The Administrative Core will also coordinate travel for VANDy-CdV members to attend and participate in Annual Programmatic Meetings. The third aim is to provide fiscal oversight. Vanderbilt University Medical Center is ultimately responsible for all spending decisions involving VANDy-CdV; however, the initial level of fiscal oversight will be the responsibility of the Administrative Core. The fourth aim is to manage intellectual property, resource and reagent distribution, and transmittal of data to public databases. Opportunities relating to intellectual property across the projects and cores will be handled by the Administrative Core in conjunction with the Vanderbilt Center for Commercialization and Technology Transfer (CTTC). The Administrative Core also will ensure that all reasonable requests for reagents from any VANDy-CdV program are satisfied within a timely manner.