Novel targets for atherosclerosis therapy

动脉粥样硬化治疗的新靶点

• 批准号: nhmrc : 1049100
• 负责人: Dr Sophocles Chrissobolis
• 金额: $ 23.21万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-targets-atherosclerosis-therapy/112058
• 关键词: Novel; targets; atherosclerosis; therapy

Cardiovascular disease is a leading cause of death in Australia, accounting for 36% of all deaths in 2004-05. Diseased blood vessels are its most common form, and the underlying process is atherosclerosis. Atherosclerosis is characterised by plaque formation in blood vessels. Plaque formation is problematic, and may lead to blood vessel blockage. We aim to identify novel targets that prevent plaque formation.

心血管疾病是澳大利亚的主要死因，2004- 2005年占所有死亡人数的36%。血管扩张是其最常见的形式，其基础过程是动脉粥样硬化。动脉粥样硬化的特征在于血管中的斑块形成。斑块形成是有问题的，并且可能导致血管阻塞。我们的目标是确定新的目标，防止斑块形成。