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HIV PrEP Perspectives of Liberian Adolescent Girls and Young Women and their Providers

利比里亚少女和年轻妇女及其提供者的 HIV PrEP 观点

基本信息

批准号：
10619271
负责人：
Onyema E. Ogbuagu
金额：
$ 23.85万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-02-15 至 2025-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10619271
关键词：
AIDS prevention Acquired Immunodeficiency Syndrome Address Administrator Africa Africa South of the Sahara African Attention Attitude Authorization documentation Behavioral Clinic Collaborations Complex Consensus Country County Cross-Sectional Studies Data Decision Making Development Disadvantaged Eastern Africa Eligibility Determination Evaluation Face Family Planning Female Adolescents Formulation Goals HIV HIV Infections HIV vaccine Health Health Personnel Injecting drug user Intervention Interview Investigation Knowledge Leadership Liberia Liberian Male Circumcision Men&apos s Role Methods Modality Modeling Motivation Oral Participant Perception Perinatal Pharmaceutical Preparations Physicians Policy Maker Population Populations at Risk Prevalence Prevention Process Program Development Provider Public Health Reporting Reproductive Health Services Research Infrastructure Research Methodology Research Personnel Respondent Risk Risk Reduction Rural Scientist Site Southern Africa Structure Techniques Testing Vertical Disease Transmission Vulnerable Populations Woman Work authority condoms design experience falls girls implementation strategy infection risk informant interest intervention mapping male men men who have sex with men pre-exposure prophylaxis preference programs recruit risk perception rural area sexual violence sexually active adolescent skills social transgender women treatment as prevention uptake urban area willingness young woman

项目摘要

PROJECT SUMMARY/ABSTRACT Pre-Exposure Prophylaxis (PrEP) is becoming increasingly available in sub-Saharan Africa (SSA) and as a highly effective and user-controlled intervention for HIV prevention holds promise for those most at risk of infection including adolescent girls and young women (AGYW). However, most of the increased uptake of PrEP in SSA has been in a handful of countries with the world’s highest HIV rates, and where the HIV prevalence can influence risk perception and willingness to use PrEP. Despite the rise PrEP in these and other regions where it is available, most of those eligible for PrEP are not using it, and among those that do begin PrEP, discontinuation rates in the months after initiation is common, especially for AGYW, In West Africa, where HIV rates are lower but unacceptably high, PrEP is beginning to be rolled out. Public health authorities in Liberia have taken steps to integrate PrEP into the country’s HIV prevention programming and have recently started pilot clinics to administer PrEP to men who have sex with men, transgender women, and people who inject drugs. In 2023-24, PrEP will be expanded nationwide to include the largest key population AGYW. These policymakers are deeply interested in developing PrEP programming that is preference-sensitive and reflects determinants of PrEP engagement for AGYW in the West African context, which is distinct from those of other regions of Africa. Therefore, we propose to obtain an in-depth understanding of the PrEP perceptions and preferences among urban and rural AGYW in Liberia, their male partners, and healthcare providers – applying the situated Information, Motivation, and Behavioral Skills (sIMB) model to guide our investigations. In close collaboration with PrEP planners, we will then use Intervention Mapping framework processes to directly apply the formative data to the development of implementation planning for PrEP for AGYW. The resulting implementation options will serve as a roadmap for the critical next stage of PrEP roll-out in Liberia and serve as a model for similar settings.

项目总结/摘要暴露前预防（PrEP）在撒哈拉以南非洲（SSA）越来越多，预防艾滋病毒的高度有效和用户控制的干预措施为那些最有可能感染艾滋病毒的人带来了希望。感染，包括少女和年轻妇女（AGYW）。然而，大多数增加的PrEP吸收在撒哈拉以南非洲，艾滋病毒感染率在世界上最高的少数几个国家，影响风险认知和使用PrEP的意愿。尽管PrEP在这些地区和其他地区有所增加，可用，大多数符合PrEP条件的人都没有使用它，并且在那些开始PrEP的人中，在开始后的几个月内发生率是常见的，特别是对于AGYW，在西非，艾滋病毒感染率较低，但高得令人无法接受，PrEP已开始推广。公共利比里亚卫生当局已采取措施，将PrEP纳入该国的艾滋病毒预防规划最近开始试点诊所，向男男性行为者、变性妇女、和注射毒品的人在2023-24年，PrEP将在全国范围内扩大，以包括最大的重点人群 AGYW。这些政策制定者对制定对偏好敏感的PrEP方案非常感兴趣并反映了在西非背景下AGYW参与PrEP的决定因素，这与非洲其他地区。因此，我们建议深入了解PrEP 利比里亚城市和农村AGYW及其男性伴侣和医疗保健的看法和偏好提供者-应用情境信息，动机和行为技能（sIMB）模型来指导我们的调查事务所在与PrEP规划者的密切合作下，我们将使用干预映射框架直接将形成性数据应用于为AGYW制定PrEP实施计划的流程。由此产生的实施方案将作为在利比里亚推广PrEP的关键下一阶段的路线图并作为类似环境的典范。