4th International Epithelial Meschymal Transition Meeting

描述（由申请人提供）： 第四届上皮间充质干细胞国际会议要求部分支持 过渡（EMT）。EMT是用于从上皮片形成三维结构的基本细胞过程。它通常在发育中作为涉及原肠胚形成、神经嵴形成、心脏瓣膜形成、冠状血管形成和腭融合、胰岛发育和其他发育过程的过程而被发现。出生后，EMT是伤口愈合的正常组成部分，并在器官纤维化（心脏，肝脏和肾脏）和癌症转移的病理学中复发。本次会议旨在将发育生物学家与病理学家和肿瘤学家聚集在一起，比较EMT在其发生的各种地方的共同和不同元素。与会者将讨论信号转导，基因调控，细胞-细胞和细胞-ECM粘附，细胞骨架组织的变化和EMT调控的新方面。时间表包括一个由实地资深调查员组成的核心小组和从摘要中选出的大量发言者。从摘要中选择演讲者将为该计划提供一种前沿的感觉。会议的目标是建立跨三个学科的数据和技术的集成。要求提供资金，以支持会议的运作，并为少数群体和女性发言者提供旅费支助，并减少学生与会者的登记费用。(End摘要）

DESCRIPTION (provided by applicant): Partial support is requested for the 4th International Meeting on Epithelial Mesenchymal Transition (EMT). EMT is a basic cellular process utilized to form three dimensional structures from an epithelial sheet. It is normally found in development as a process involved in gastrulation, neural crest formation, heart valve formation, coronary vessel formation and palate fusion, pancreatic islet development and other developmental processes. Postnatally, EMT is a normal component of wound healing and reoccurs in the pathologies of organ fibrosis (heart, liver, and kidney) and cancer metastasis. This meeting is designed to bring together developmental biologists with pathologists and oncologists to compare the common and disparate elements of EMT in the variety of places that it occurs. Participants will discuss signal transduction, gene regulation, cell-cell and cell-ECM adhesion, changes in cytoskeletal organization and novel aspects of EMT regulation. The schedule is comprised of a core of established investigators in the field and a large number of speakers to be selected from abstracts. Selection of speakers from abstracts will provide a cutting edge feel to the program. The objective of the meeting is to build an integration of data and techniques across the three disciplines. Funds are requested to support meeting operation as well as travel support for minority and female speakers and a reduction in registration costs for student participants. (End of Abstract)