Obesity and AF: characterisation and reversibility of the clinical substrate

肥胖和房颤：临床基质的特征和可逆性

• 批准号: nhmrc : 1113207
• 金额: $ 23.05万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/obesity-af-characterisation-clinical-substrate/663242
• 关键词: Obesity; AF; characterisation; reversibility; clinical

Over the last 5 years, I have characterized the atrial fibrillation (AF) substrate in obese sheep model. My goal is now to translate this work to the clinic and confirm the mechanisms of AF in obese patients and their reversibility with weight reduction with a specific aim to identify targets for intervention. Over this period, I intend to establish myself as an independent researcher with the long-term goal of developing effective prevention and management strategies for AF in obesity.

在过去的5年里，我在肥胖羊模型中描述了心房颤动（AF）底物。我现在的目标是将这项工作转化为临床，并确认肥胖患者房颤的机制及其与体重减轻的可逆性，以确定干预目标。在此期间，我打算成为一名独立的研究人员，长期目标是为肥胖患者制定有效的房颤预防和管理策略。