Obesity and AF: characterisation and reversibility of the clinical substrate

肥胖和房颤：临床基质的特征和可逆性

• 批准号: nhmrc : GNT1113207
• 负责人: Dr Rajiv Mahajan
• 金额: $ 33.72万
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/obesity-af-characterisation-clinical-substrate/1346835
• 关键词: Obesity; AF; characterisation; reversibility; clinical

Over the last 5 years, I have characterized the atrial fibrillation (AF) substrate in obese sheep model. My goal is now to translate this work to the clinic and confirm the mechanisms of AF in obese patients and their reversibility with weight reduction with a specific aim to identify targets for intervention. Over this period, I intend to establish myself as an independent researcher with the long-term goal of developing effective prevention and management strategies for AF in obesity.

在过去的 5 年里，我在肥胖绵羊模型中描述了心房颤动 (AF) 基质的特征。我现在的目标是将这项工作转化为临床，并确认肥胖患者的 AF 机制及其随着体重减轻的可逆性，具体目的是确定干预目标。在此期间，我打算将自己打造成一名独立研究人员，其长期目标是为肥胖症中的房颤制定有效的预防和管理策略。