Johns Hopkins Retinal Degenerations and Visual Electrophysiology Conference 2023.
2023 年约翰霍普金斯大学视网膜变性和视觉电生理学会议。
基本信息
- 批准号:10753624
- 负责人:
- 金额:$ 7万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-09-01 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:AffectAgreementAllogenicAnimal ModelAnimalsArtificial IntelligenceAwardBaltimoreBasic ScienceBlindnessCell TherapyCellsClinicalClinical ResearchClinical TrialsCollaborationsComplementConsensusDataDetectionDeveloping CountriesDevelopmentDiagnosisDiseaseDisease ProgressionElectrophysiology (science)EquityEthicsFaculty WorkshopFailureFosteringFundingGene therapy trialGenesGoalsHumanHuman Cell LineImmunosuppressionIndividualIndustryInheritedInternationalKnowledgeLaboratoriesLaboratory ResearchLeadLearningMarylandMicroelectrodesModalityMolecularNanotechnologyOperative Surgical ProceduresOrganoidsOutcome MeasureParticipantPathogenesisPatientsPerimetryPersonsPharmacotherapyPhasePhase III Clinical TrialsPhenotypeProtocols documentationRecommendationRecurrenceResearchResearch PersonnelResearch SubjectsRetinaRetinal DegenerationRetinal DiseasesRetinal DystrophyScheduleScienceScientistSeriesSerious Adverse EventSocietiesSourceStem cell transplantTestingTherapeuticTherapeutic AgentsTranslational ResearchTravelTreatment FailureTreatment outcomeUnderrepresented MinorityUpdateVisionVisualVisual impairmentWomanantioxidant therapybase editingcareerclinical careclinical translationcomputer studiesdesignepidemiology studyequity, diversity, and inclusionfirst-in-humanfunctional outcomesgene therapygenome editinghearing impairmenthuman subjectimplantationin vitro Modelinsightmeetingsmultidisciplinarynanomedicineneurophysiologyneuroprotectionnovelnovel therapeuticspre-clinicalpreventprogramsreconstructionretinal progenitor cellstem cell gene therapystem cell therapystem cellssuccesssymposiumtherapy developmenttranslational studytreatment strategy
项目摘要
Project Summary/Abstract
This application seeks to support three biennial editions of the Johns Hopkins Retinal Degenerations and Visual
Electrophysiology Conference. These meetings will continuously update early-stage investigators, trainees,
clinicians, and scientists on the latest translational and clinical research on Inherited retinal diseases (IRDs). In
addition, the conference will address multiple identified gaps in knowledge in interpreting visual function tests,
including electrophysiology and microperimetry. The meetings will be held biannually in September in Baltimore,
Maryland. The specific aims covered by this conference include 1) understanding the cellular and molecular
basis of selected IRDs, 2) reviewing the recommendations from the Society of Clinical Electrophysiology of
Vision (ISCEV) regarding visual neurophysiology testing, 3) reviewing the structural and functional outcome
measures of IRDs, including those relevant to research subjects with ultra-low vision, 4) analyzing data and
results from current treatments in development, especially those in Phase I, II, and III clinical trials and large
animal studies, with an emphasis on retinal stem cells and gene therapy, and other treatment modalities, and 5)
reviewing aspects relating to equitable access to clinical care and research for IRD patients, and ethical
considerations unique to people with vision loss due to IRDs. The requested funds will support the attendance
of trainees and early-career investigators, travel awards, and diversity awards to support women, under-
represented minorities (URMs), and international participants, including those from developing countries. These
meetings will be an ideal opportunity for trainees of diverse backgrounds, early-stage investigators, under-
represented minorities, and international trainees to network and learn from leaders in the field of retinal
degeneration. In addition, we hope this meeting will encourage multidisciplinary and international collaboration
between clinicians and investigators to develop novel therapies and clinical trials end points.
项目摘要/摘要
这项申请寻求支持约翰霍普金斯大学的视网膜变性和视觉的三个两年一次的版本
电生理学会议。这些会议将不断更新早期调查人员、实习生、
临床医生和科学家对遗传性视网膜疾病(IRD)的最新翻译和临床研究。在……里面
此外,会议将解决在解释视觉功能测试方面发现的多个知识差距,
包括电生理学和微视野检查。会议将于9月在巴尔的摩举行,一年两次,
马里兰州。本次会议的具体目标包括:1)了解细胞和分子
选定的IRD的基础,2)审查来自临床电生理学会的建议
关于视觉神经生理学测试的视觉(ISCEV),3)回顾结构和功能结果
IRDS的测量,包括与超低视力研究对象相关的测量,4)分析数据和
来自当前正在开发的治疗方法的结果,特别是那些处于I期、II期和III期临床试验和大型
动物研究,重点是视网膜干细胞和基因治疗,以及其他治疗方式,以及5)
审查与IRD患者公平获得临床护理和研究有关的方面,以及伦理
由于IRDS而导致视力丧失的人所特有的考虑。所申请的资金将用于支持出席
实习生和早期职业调查人员、旅行奖和多样性奖,以支持妇女,在以下方面-
有代表性的少数群体和国际参与者,包括来自发展中国家的参与者。这些
会议将是不同背景的实习生、早期调查人员、以下人员的理想机会-
代表少数族裔和国际受训人员与视网膜领域的领导人建立网络并向其学习
退化。此外,我们希望这次会议将鼓励多学科和国际合作。
临床医生和研究人员之间的合作,以开发新的疗法和临床试验终点。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('MANDEEP SINGH', 18)}}的其他基金
Developing photoreceptor repair for macular degeneration therapy.
开发用于黄斑变性治疗的光感受器修复。
- 批准号:
10490297 - 财政年份:2021
- 资助金额:
$ 7万 - 项目类别:
Developing photoreceptor repair for macular degeneration therapy.
开发用于黄斑变性治疗的光感受器修复。
- 批准号:
10280491 - 财政年份:2021
- 资助金额:
$ 7万 - 项目类别:
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