课题基金 / 基金详情

Immune Function and Biodefense in Children, Elderly, and Immunocrompromised

Immune Function and Biodefense in Children, Elderly, and Immunocrompromised
儿童、老年人和免疫功能低下者的免疫功能和生物防御
批准号:
7941277
负责人:
金额:
$124.5万
依托单位国家:
美国
项目类别:
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-09-30 至 2010-09-29

项目摘要

项目成果

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中文摘要
翻译
儿童、老年人和免疫缺陷人群的免疫功能和生物防御计划将开发新的方法来保护或治疗面临生物恐怖威胁的免疫缺陷个体。该研究计划将包括确定导致这些人群感染易感性增加或疫苗效力降低的生物机制,以及测试旨在提高安全性或有效性的治疗方法的临床研究。这项研究将有助于预防儿童、老年人和免疫功能低下人群的传染病。 这份合同包括对流感、尼帕病毒、埃博拉病毒、痘病毒的研究。
英文摘要
The Immune Function and Biodefense in Children, Elderly, and Immunocrompromised Populations program will develop novel methods for protecting or treating immunocrompromised individuals at risk from bioterror threats. The research program will cover the identification of biological mechanisms responsible for increased susceptibility to infection or decreased effectiveness of vaccines in these populations, as well as clinical research to test treatments designed to increase safety or efficacy. This research will lead to the prevention of infectious disease in children, the eldery and immunocompromised populations. This contract includes studies on influenza, nipah virus, ebola virus, poxvirus.
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原生动物四膜虫生殖小核(germline nucleus)体功能(somatic function)的分子基础研究