Sickle Cell Scholar Component
镰状细胞学者组件
基本信息
- 批准号:7821239
- 负责人:
- 金额:$ 22.33万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-04-28 至 2012-03-31
- 项目状态:已结题
- 来源:
- 关键词:AreaBiochemical GeneticsBiochemistryClinicalClinical InvestigatorClinical ResearchClinical TrialsClinical Trials DesignDataDatabasesDevelopmentDevelopment PlansDisciplineDiseaseDoctor of PhilosophyEducational CurriculumEnsureEpidemiologyFacultyFunctional disorderFutureGeneticGenomicsGoalsHealthcareImmunogeneticsInvestigationJointsLaboratoriesLeadLeadershipLearningMentored Clinical Scientist Development ProgramMentorsMentorshipMolecular BiologyMolecular GeneticsNCI Scholars ProgramPhysiciansResearchResearch EthicsResearch PersonnelResearch Project GrantsResearch TrainingScientistSickle CellSickle Cell AnemiaStigmataStructureTechniquesTrainingTraining ProgramsTranslational ResearchUnited States National Institutes of HealthUniversitiesVascular DiseasesWashingtonWorkburden of illnesscare deliverycareercareer developmentdesignimprovedinnovationinterestiron metabolismmultidisciplinaryprogramsskillssocial stigmastatisticssuccesstool
项目摘要
The Scholar will spend at least 75 percent of his/her effort in sickle cell anemia-related research under the
leadership of Dr. Luban, an established clinical investigator who also directs faculty training and mentorship at
CNMC. Dr. Luban in conjunction with the physicians and scientist of WACSCC will develop a carefully
planned, individualized research training program designed to ensure that the Scholar becomes an
independent physician and/or biomedical researcher focused on critical translational and clinical questions
related to sickle cell disease. An individualized career development plan (ICDP) (Appendix A) will be
developed for the Sickle Cell Scholar and will encompass three major components: core curriculum, laboratory
training and translational applications in the clinical setting.
The first component is formal course work including a variety of disciplines: statistics, epidemiology, clinical
trial design, regulatory aspects of clinical investigation, research ethics, scientific tools of clinical investigation,
analytical techniques in clinical investigation, and principles and techniques of biochemistry, molecular biology
and molecular genetics. These courses will be provided through the HU (RR010284) and CNMC (RR020359)
Clinical Research Centers and the HU Research Scientist Program (R25HL003679) augmented by our joint
K30 and associated T32 and K12 programs and by course work at HUSM and CNMC, local universities and
through selected programs at NIH
The second component provides a highly structured laboratory training program that is designed to
provide practical training in biochemistry, molecular biology, genetics and analytic techniques, and in the
analysis of clinical and laboratory data that results from bench investigations and clinical investigation
implemented at the WACSCC collaborative laboratories and GCRCs. Physician scientists and epidemiologic
researchers with interests in health care disparities and care delivery will engage in programs designed to
learn methodological approaches to data- based investigations and quantitative research.
The third component consists of developing and conducting a clinical project in sickle cell disease.
The scholar will design, implement and participate in the conduct of a mentored clinical research project. This
part of Scholar's training will ensure that he/she develops the training needed to conduct multidisciplinary
clinical research, recognize the difficulties in such studies and develop tools to ensure future success as a
clinical researcher or collaborative biomedical researcher.
The ultimate goal of the Sickle Cell Scholar program is to inspire young and/or new investigators to devote
their career to innovative and productive research that will lead to decreasing the disease burden and stigmata
of this disease.
该学者将花费至少75%的努力在镰状细胞贫血相关的研究下,
鲁班博士的领导,一个既定的临床研究者谁也指导教师培训和导师在
CNMC。鲁班博士将与WACSCC的医生和科学家一起,
有计划的,个性化的研究培训计划,旨在确保学者成为一个
专注于关键转化和临床问题的独立医生和/或生物医学研究人员
与镰状细胞病有关。个人职业发展计划(ICDP)(附录A)将
为镰状细胞学者开发,将包括三个主要组成部分:核心课程,实验室
临床环境中的培训和翻译应用。
第一部分是正式的课程工作,包括各种学科:统计学,流行病学,临床
试验设计、临床研究的监管方面、研究伦理、临床研究的科学工具,
临床研究中的分析技术,以及生物化学、分子生物学的原理和技术
和分子遗传学。这些课程将通过HU(RR 010284)和CNMC(RR 020359)提供
临床研究中心和HU研究科学家计划(R25 HL 003679)由我们的联合
K30和相关的T32和K12计划,以及HUSM和CNMC,当地大学和
通过国家卫生研究院的一些项目
第二部分提供了一个高度结构化的实验室培训计划,旨在
提供生物化学、分子生物学、遗传学和分析技术方面的实践培训,
实验室研究和临床研究的临床和实验室数据分析
在WACSCC合作实验室和GCRC实施。医生科学家和流行病学
对卫生保健差异和保健提供感兴趣的研究人员将参与旨在
学习以数据为基础的调查和定量研究的方法。
第三个组成部分包括制定和实施镰状细胞病临床项目。
学者将设计,实施和参与指导临床研究项目的进行。这
学者的培训的一部分将确保他/她开发进行多学科所需的培训
临床研究,认识到这些研究的困难,并开发工具,以确保未来的成功,
临床研究人员或合作生物医学研究人员。
镰状细胞学者计划的最终目标是激励年轻和/或新的研究人员致力于
他们的职业生涯创新和富有成效的研究,这将导致减少疾病负担和污名
这种疾病。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Victor R Gordeuk其他文献
Cabana and Camainza: Malaria-Like Syndromes of Childhood in Rural Zambia
卡巴纳和卡马因扎:赞比亚农村地区儿童疟疾样综合征
- DOI:
10.1203/00006450-199904020-00937 - 发表时间:
1999-04-01 - 期刊:
- 影响因子:3.100
- 作者:
Anita G Brennan;Godfrey Biemba;Philip E Thuma;Victor R Gordeuk;Warren E Grupe - 通讯作者:
Warren E Grupe
Victor R Gordeuk的其他文献
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{{ truncateString('Victor R Gordeuk', 18)}}的其他基金
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)
改善青少年镰状细胞护理
- 批准号:
9482318 - 财政年份:2017
- 资助金额:
$ 22.33万 - 项目类别:
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)
改善青少年镰状细胞护理
- 批准号:
9928658 - 财政年份:2016
- 资助金额:
$ 22.33万 - 项目类别:
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)
改善青少年镰状细胞护理
- 批准号:
9928286 - 财政年份:2016
- 资助金额:
$ 22.33万 - 项目类别:
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)
改善青少年镰状细胞护理
- 批准号:
10160619 - 财政年份:2016
- 资助金额:
$ 22.33万 - 项目类别:
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)
改善青少年镰状细胞护理
- 批准号:
9326337 - 财政年份:2016
- 资助金额:
$ 22.33万 - 项目类别:
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)
改善青少年镰状细胞护理
- 批准号:
9180588 - 财政年份:2016
- 资助金额:
$ 22.33万 - 项目类别:
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)
改善青少年镰状细胞护理
- 批准号:
10197197 - 财政年份:2016
- 资助金额:
$ 22.33万 - 项目类别:
Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)
改善青少年镰状细胞护理
- 批准号:
10465381 - 财政年份:2016
- 资助金额:
$ 22.33万 - 项目类别:
Washington Area Basic and Translational Research Program
华盛顿地区基础和转化研究计划
- 批准号:
7819148 - 财政年份:2009
- 资助金额:
$ 22.33万 - 项目类别:
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