California National Primate Research Center

这一更新要求支持加州国家灵长类动物研究中心的工作人员科学家，灵长类动物 服务、行政服务以及改进和现代化项目。内部和外部支助服务 校外研究计划由行政服务和灵长类服务单位提供。 这项申请的目的是：1）提供必要的基础设施支持，以成功地进行研究， 非人灵长类动物; 2）增强中心作为区域、国家和国际资源的能力; 3） 通过扩大特定的特征，增加特定特征的恒河猴用于生物医学研究的可用性 无病原体菌落。 第一个目标将通过为四个分类研究单位的20名科学家提供支持来实现：大脑， 精神和行为;生殖科学;呼吸系统疾病;和病毒学和免疫学。aids相关 研究由四个单位中的三个单位的科学家进行。总的来说，工作人员科学家担任 为一个基础广泛的计划，继续吸引来自中心以外的科学家的知识基础设施。的 附属科学家计划为非工作人员研究人员提供在CNPRC开展研究的机会， 试点研究计划是专门为初级研究人员和/或那些 对非人类灵长类动物的研究缺乏经验 目标2和3将通过拟议的设施改进以及三项资源- 本申请中提出的相关研究项目，将集中于：a）使用生物声学评估， 灵长类动物管理; B）采用生殖策略以增强室内繁殖群体的管理; 和c）开发用于分枝杆菌检测的新方法。 本次更新还提出了六个核心科学服务单位：计算成像，内分泌，免疫学， 吸入暴露、病原体检测和行为评估。这些服务单位将提供专门知识， 资源，以支持在中心的核心和合作研究。

This renewal requests support for the California National Primate Research Center's Staff Scientists, Primate Services, Administrative Services, and Improvement and Modernization projects. Support services for intra- and extramural research programs are provided by the Administrative Services and Primate Services Units. The aims of this application are to: 1) provide infrastructure support essential to conduct successful research on nonhuman primates; 2) enhance the Center's ability to serve as a regional, national and international resource; 3) increase availability of specifically characterized rhesus macaques for biomedical research by expanding the specific pathogen free colony. The first aim will be carried out by providing support for 20 Staff Scientists in four categorical research units: Brain, Mind and Behavior; Reproductive Sciences; Respiratory Diseases; and Virology and Immunology. AIDS-related research is conducted by scientists from three of the four Units. Collectively, the Staff Scientists serve as the intellectual infrastructure for a broad-based program that continues to attract scientists from outside the Center. The Affiliate Scientist Program provides opportunities for non-Staff investigators to conduct research at CNPRC, and the Pilot Research Program is especially designed to provide research opportunities to junior investigators and/or those inexperienced with nonhuman primate research. Aims 2 and 3 will be accomplished by facilities improvements that are proposed, as well as by the three Resource- Related Research Projects proposed in this application, which will focus on: a) using bioacoustic assessment for primate management; b) employing reproductive strategies for enhancing management of the indoor breeding colony; and c) developing novel methods for Mycobacteria detection. Six Core Science Service Units are also proposed in this renewal: Computational Imaging, Endocrine, Immunology, Inhalation Exposure, Pathogen Detection and Behavior Assessment. These service units will provide the expertise and resources to support both core and collaborative research at the Center.