课题基金 / 基金详情

SPRINT

SPRINT
短跑
批准号：
7980633
负责人：
Suzanne Oparil
金额：
$67.01万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-09-14 至 2018-09-13
来源：
https://reporter.nih.gov/project-details/7980633
关键词：
SPRINT

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中文摘要
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英文摘要
The Systolic Blood Pressure Intervention Trial, (SPRINT) contractor will conduct a multicenter, randomized clinical trial to determine whether treating systolic blood pressure to a lower goal than currently recommended, will reduce cardiovascular disease. The Clinical Center Networks (CCNs) shall provide leadership and oversee the clinical sites for inclusion of the SPRINT CCN hub and the Memory and Cognition in Decreased Hypertension (MIND) substudy. The objectives of SPRINT-MIND shall include, but are not limited to: (1) Cognitive functioning to determine whether treating to a SBP lower goal than currently recommended will reduce the incidence of cognitive decline and incidence of probable dementia; (2) Imaging, to determine whether treating to a SBP lower goal than currently recommended will reduce the incidence of structural central nervous system abnormalities related to vascular dementia, and rate of decline in total brain volume; and (3) Diagnosis of probable dementia, to screen all SPRINT participants annually for probable dementia.
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会议论文
30th Annual Vascular Biology and Hypertension Symposium
Pregnancy as a Window to the Future: Outcomes of Antihypertensive Therapy and Superimposed Preeclampsia in Pregnant Women with Mild Chronic Hypertension (CHAP Maternal Follow-up Study)
Pregnancy as a Window to the Future: Outcomes of Antihypertensive Therapy and Superimposed Preeclampsia in Pregnant Women with Mild Chronic Hypertension (CHAP Maternal Follow-up Study)
Pregnancy as a Window to the Future: Outcomes of Antihypertensive Therapy and Superimposed Preeclampsia in Pregnant Women with Mild Chronic Hypertension (CHAP Maternal Follow-up Study)
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