RENEWABLE CAPTORS FOR ADDICTION-RELEVANT PROTEINS

该项目的目标是开发针对成瘾相关蛋白的可再生抗体。到目前为止，单抗已成为蛋白质捕获的主要亲和剂。然而，用传统的杂交瘤技术开发单抗既耗时又昂贵。体外产生的可再生抗体是一种很好的单抗替代品，因为这些可再生抗体也具有高特异性和亲和力，并且可以经济有效地生产。

The objective of this project is to develop renewable antibodies against addiction-relevent proteins. Monoclonal antibodies (mAbs) have been the major affinity reagents as protein captures to date. However, development of mAbs with conventional hybridoma technology is time-consuming and costly. In vitro generated renewable antibodies are an excellent alternative to mAb, since these renewable antibodies are also of high specificity and affinity, and can be cost-effectively producted.