THYROID ACTION IN THE HEART

甲状腺在心脏中的作用

• 批准号: 7957622
• 负责人: Wolfgang H Dillmann
• 金额: $ 1.56万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-15 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7957622
• 关键词: Cardiac Myocytes; Computer Retrieval of Information on Scientific Projects Database; Endothelial Cells; Funding; Grant; Heart; Image Analysis; Institution; Protein Isoforms; Research; Research Personnel; Resources; Role; Source; Thyroid Gland; Thyroid Hormone Receptor; United States National Institutes of Health; cell type; design

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project is designed to clarify the mechanisms which underlie Thyroid hormone receptor (T3R) isoform specific effects in the heart. We will investigate the functional role of T3R in the cardiac myocytes and heart microvascular endothelial cells. In addition, the distribution of the different isoform of T3Rs will be determined in the different cell types.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该项目旨在阐明甲状腺激素受体（T3 R）亚型在心脏中特异性作用的机制。我们将探讨T3受体在心肌细胞和心脏微血管内皮细胞中的功能作用。此外，将确定T3 R的不同同种型在不同细胞类型中的分布。