Optimal protein dose to attenuate muscle atrophy, improve functional recovery and increase survival in critically ill patients

减轻肌肉萎缩、改善功能恢复并提高危重患者生存率的最佳蛋白质剂量

• 批准号: nhmrc : GNT1157341
• 负责人: Dr Leeanne Chapple
• 金额: $ 32.72万
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/optimal-protein-dose-ill-patients/1349230
• 关键词: Optimal; protein; dose; attenuate; muscle

Many survivors of critical illness have impaired physical function and quality of life and these deficits persist well after discharge. Optimal protein delivery, fed via a gastric tube, has the potential to reduce muscle wasting and, hence, improve functional outcomes. The proposed research will provide a comprehensive understanding of how protein is handled by the body during critical illness and define how much protein should be delivered to aid long-term recovery.

许多危重疾病的幸存者身体机能和生活质量受损，并且这些缺陷在出院后仍持续存在。通过胃管喂养的最佳蛋白质输送有可能减少肌肉消耗，从而改善功能结果。拟议的研究将全面了解身体在危重疾病期间如何处理蛋白质，并确定应输送多少蛋白质以帮助长期康复。