Pharmaceutical Sciences and Pharmacogenomics

药物科学和药物基因组学

• 批准号: 7892102
• 负责人: FRANCIS C. SZOKA
• 金额: $ 25.99万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7892102
• 关键词: Pharmacogenomics; Pharmacologic Substance; Science

DESCRIPTION (provided by applicant): The Pharmaceutical Sciences and Pharmacogenomics Graduate Program (PSPG) is a cross-disciplinary program that consists of scientists at the University of California, San Francisco (UCSF) working in pharmaceutical sciences, computation and contemporary genetics. This Program encompasses the areas of molecular pharmacology related to drug development including: drug action, drug transport, drug metabolism and drug/gene delivery. The Program also includes the areas of pharmacokinetic/dynamic modeling, pharmacogenomics and bioinformatics applied to genetics/genomics. The Program offers training in these research areas through a core curriculum that encourages a breadth of knowledge about these fields and an elective curriculum that provides in-depth education on specific topics or techniques. Students participate in an ethical conduct in science course. The program immerses young scientists in the culture of science through a seminar program in pharmacogenomics, an annual retreat and seminars from industrial scientists. Students are recruited into the program with undergraduate degrees in the basic sciences and from Doctor of Pharmacy programs. There are 50 students in the program and approximately 10% of the students come from under represented groups. The program capacity was increased in 2000 from 35 students to 60 students and we anticipate reaching the 60 student capacity in 2012. There are 49 training faculty. Our program is one of the very few in the World with faculty expertise that spans the fields of pharmaceutics, genetics and computation; hence the training program is ideally situated to educate future scientific leaders in the emerging research areas at the intersection of these disciplines. The integrative approach has resulted in Ph.D. graduates who have the insights and quantitative scientific tools required for success in the rapidly advancing fields of drug development and pharmacogenomics; consequently graduates from the program are in high demand in academia, government and industry.

描述（由申请人提供）：药物科学和药物基因组学研究生课程（PSPG）是一个跨学科的计划，由加州大学弗朗西斯科分校（UCSF）的科学家组成，从事药物科学，计算和当代遗传学。 该计划包括与药物开发相关的分子药理学领域，包括：药物作用，药物转运，药物代谢和药物/基因递送。该计划还包括药代动力学/动态建模，药物基因组学和生物信息学应用于遗传学/基因组学领域。 该计划通过核心课程提供这些研究领域的培训，鼓励对这些领域的广泛知识和选修课程，提供对特定主题或技术的深入教育。学生参与科学课程中的道德行为。该计划通过药物基因组学研讨会计划，年度务虚会和工业科学家研讨会，使年轻科学家沉浸在科学文化中。 学生被招募到该计划与本科学位的基础科学和药学博士课程。该计划有50名学生，大约10%的学生来自代表性不足的群体。该计划的能力在2000年从35名学生增加到60名学生，我们预计在2012年达到60名学生的能力。有49个培训机构。 我们的计划是世界上为数不多的跨越制药，遗传学和计算领域的教师专业知识之一;因此，培训计划非常适合在这些学科交叉的新兴研究领域教育未来的科学领导者。综合方法导致了博士学位。谁拥有在药物开发和药物基因组学的快速发展领域取得成功所需的见解和定量科学工具的毕业生;因此，该计划的毕业生在学术界，政府和工业界的需求很高。