Core Center for Quantitative Biology

定量生物学核心中心

• 批准号: 7936185
• 负责人: Bradley John Roth
• 金额: $ 33.61万
• 依托单位: OAKLAND UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7936185
• 关键词: Bioinformatics; Biology; Biomedical Engineering; Biomedical Research; Cell Nucleus; Collection; Doctor of Philosophy; Engineering; Faculty; Funding; Goals; Mathematical Biology; Medicine; Methods; Modeling; Positioning Attribute; Publishing; Recruitment Activity; Research; Research Personnel; Science; Systems Biology; Translational Research; Universities; Work; biological systems; medical schools; member; programs; public health relevance

DESCRIPTION (provided by applicant): The goal of this proposal is to develop a Core Center in Quantitative Biology at Oakland University. To strengthen this Core Center, a new faculty member will be recruited to perform interdisciplinary and translational research. This Core Center will build on existing strengths at Oakland University, including the recently established Engineering Biology undergraduate major, plans for a PhD program in Quantitative Biology, and the new Oakland University William Beaumont School of Medicine. The focus on Quantitative Biology for the proposed Core Center was selected to take advantage of existing strengths at Oakland University. A nucleus of superb faculty are actively working in mathematical biology, bioengineering, and numerical modeling. Many of the faculty are members of the Center for Biomedical Research, publish extensively, and are externally funded. They represent an outstanding collection of biomedical researchers, often in their early years at OU, which the Core Center will help unify and support. The Core Center will be administered by the Oakland University Center for Biomedical Research (CBR). The current director of the CBR is also the PI for this proposal and is therefore in an ideal position to supervise and administer this effort. A university-wide search committee will be established to select the new faculty member. Highest priority will be given to applicants who can serve as bridges between existing research programs. In addition, applicants are sought who can perform translational research that will strengthen the new medical school. PUBLIC HEALTH RELEVANCE (provided by applicant): Science is becoming more and more interdisciplinary, and our proposed Core Center is inherently interdisciplinary. Furthermore, biology is becoming increasingly quantitative, with fields such as "system biology" and "bioinformatics" growing at a rapid rate. This Core Center will catalyze such a change in the very methods used to study biological systems.

描述（由申请人提供）：本提案的目标是在奥克兰大学建立一个定量生物学核心中心。为了加强这一核心中心，将招募一名新的教师进行跨学科和翻译研究。这个核心中心将建立在奥克兰大学现有的优势，包括最近成立的工程生物学本科专业，计划在定量生物学博士课程，以及新的奥克兰大学威廉博蒙医学院。 重点定量生物学为拟议的核心中心被选中，以利用现有的优势在奥克兰大学。一流的教师的核心积极从事数学生物学，生物工程和数值建模。许多教师是生物医学研究中心的成员，广泛发表，并得到外部资助。他们代表了生物医学研究人员的杰出集合，通常是在他们的早年在斯坦福大学，核心中心将帮助统一和支持。 核心中心将由奥克兰大学生物医学研究中心（CBR）管理。CBR的现任主任也是该提案的PI，因此处于监督和管理这一工作的理想位置。将成立一个全校范围的遴选委员会来挑选新的教员。最高优先权将给予申请人谁可以作为现有的研究项目之间的桥梁。此外，申请人寻求谁可以进行翻译研究，将加强新的医学院。 公共卫生相关性（由申请人提供）：科学正变得越来越跨学科，我们建议的核心中心本质上是跨学科的。此外，生物学正变得越来越量化，如“系统生物学”和“生物信息学”等领域正在快速增长。这个核心中心将催化用于研究生物系统的方法的变化。

项目成果

A model of HIV-1 infection with two time delays: mathematical analysis and comparison with patient data.

• DOI: 10.1016/j.mbs.2011.11.002
• 发表时间: 2012-01
• 期刊: Mathematical biosciences
• 影响因子: 4.3
• 作者: Pawelek KA;Liu S;Pahlevani F;Rong L
• 通讯作者: Rong L