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中文摘要
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描述(申请人提供):这项计划的长期目标是在加州大学旧金山分校建立一个世界级的化学生物学小组。为了实现这一目标,我们的目标是招聘一名新的教员,以加强和扩大加州大学旧金山分校药物化学系的化学生物学小组。处于化学和生物之间的科学一直是我们系的核心力量。加州大学旧金山分校的化学生物学小组开发化学工具和技术,以解决卫生保健中涉及的关键生物学问题。加州大学旧金山分校做出了发展和培育化学生物学集团的长期承诺,因为该领域将对未来的生物医学科学和制药应用产生重大影响。招聘过程将使用特定的大学强制程序和政策来完成,这些程序和政策强调公平和公开的搜索,以找到最合格的个人。由于最近的经济形势,可用于招聘新教师的启动资金已被严重削减。来自国家和私人捐赠者的资金都在枯竭。与此同时,药物化学系有两个空缺的化学生物学职位,但缺乏这些职位的启动资金。获得初级教员的启动资金对于我们继续在加州大学旧金山分校建立一个世界级的化学生物学小组至关重要。
英文摘要
DESCRIPTION (provided by applicant): The long-term objective of this proposal is to build a world-class Chemical Biology group at UCSF. Towards that goal, we aim to recruit a new faculty member to strengthen and expand the Chemical Biology group in the Department of Pharmaceutical Chemistry at UCSF. Science at the interface between chemistry and biology has been the core strength of our department. The Chemical Biology group at UCSF develops chemical tools and technologies to address critical biological problems involved in health care. UCSF has made a long-term commitment to develop and nurture the Chemical Biology group because of the major impact this field will have on future biomedical science and pharmaceutical applications. The recruitment process will be done using specific university mandated procedures and policies that emphasize a fair and open search to find the most highly qualified individual. Available startup funds for the hiring of new faculty have been severely curtailed due to the recent economic situation. Funds from the state and private donors alike are drying up. Meanwhile, the Dept of Pharmaceutical Chemistry has two open chemical biology positions but lacks start-up funds for these positions. Obtaining start-up funding for junior faculty is critical for us to continue to build a world-class Chemical Biology group here at UCSF.
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Surfaceomic technologies and antibodies to probe cell surface proteomes and their interactomes at unprecedented small scale and high-resolution
Discovering how oncogenes remodel the surfaceome of cells
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