Center of Excellence in Biobehavioral Approaches to Symptom Management

P30 症状管理生物行为方法卓越中心 (CEBASM) 建立在我们成功的 P20 生物行为临床研究探索中心 (CBCR, P20 NR008988, 2004-2009) 的基础上。CEBASM 将利用 CBCR 与症状管理和生物行为结果相关的协同作用，以及为该中心收集的资源和开发的系统并将其扩展到生物行为模型、方法和分析的高级应用，旨在了解与以疲劳为重点的症状管理相关的生物行为机制、干预措施和结果。拟议的 P30 卓越中心的具体目标是： 1）通过集中针对症状管理的生物行为临床研究的研究资源和基础设施，扩大开展护理研究的科学家的生物行为研究能力； 2) 推进不同人群症状管理的生物行为方法，包括疲劳及其相关症状； 3）促进独立的、研究者发起的生物行为研究的生物行为计划的开发和扩展，这些生物行为研究具有疲劳的共同主题； 4）建立一个成熟的症状管理可持续生物行为研究环境，该环境以临床为重点，本质上是跨学科的。该中心将通过生物行为科学、生物行为测量以及数据服务和分析的核心工作以及实施五个资助的研究项目来实现其目标，这些项目研究患有纤维肌痛的女性、患有乳腺癌的女性、孕妇、有心脏代谢风险的女性以及患有镰状细胞病的青少年和年轻人的疲劳。该中心将指导当前和不断发展的生物行为科学领域的开发、整合、综合和传播，包括疲劳及相关现象的测量和数据分析方面的进展，并将为更大的生物行为研究界的科学家提供咨询。

The P30 Center of Excellence for Biobehavioral Approaches to Symptom Management (CEBASM) builds on our successful P20 Exploratory Center for Biobehavioral Clinical Research (CBCR, P20 NR008988, 2004- 2009).The CEBASM will take advantage of the synergy developed via the CBCR related to symptom management and biobehavioral outcomes as well as resources garnered and systems developed for that Center and expand them to advanced application of biobehavioral models, methods, and analyses aimed at understanding biobehavioral mechanisms, interventions, and outcomes related to symptom management with a focus on fatigue. The specific aims of the proposed P30 Center of Excellence are to: 1) expand biobehavioral research capacity for scientists conducting nursing research by centralizing research resources and infrastructure for biobehavioral clinical research focused on symptom management; 2) advance biobehavioral approaches for symptom management, including fatigue and its associated symptoms, in diverse populations; 3) facilitate the development and expansion of biobehavioral programs of independent, investigator-initiated biobehavioral research that have a common theme of fatigue; and 4) establish a mature environment of sustainable biobehavioral research in symptom management that is clinically focused and interdisciplinary in nature. The Center will enact its aims through the work of its cores for Biobehavioral Science, Biobehavioral Measurement, and Data Services and Analysis and through the implementation of five funded research projects studying fatigue in women with fibromyalgia, women with breast cancer, pregnant women, women with cardiometabolic risk, and adolescents and young adults with sickle cell disease. The Center will guide the development, integration, synthesis, and dissemination of current and evolving biobehavioral scientific domains, including advances in measurement and data analysis of fatigue and associated phenomena and will provide consultation to scientists in the larger biobehavioral research community.