Center of Excellence in Biobehavioral Approaches to Symptom Management

P30症状管理生物行为方法卓越中心(CEBASM)建立在我们成功的P20生物行为临床研究探索中心(CBCR，P20 NR008988,2004-2009)的基础上。CEBASM将利用通过CBCR开发的与症状管理和生物行为结果相关的协同作用，以及为该中心获得的资源和开发的系统，并将其扩展到生物行为模型、方法和分析的高级应用，旨在了解与症状管理相关的生物行为机制、干预和结果，重点是疲劳。拟议的P30卓越中心的具体目标是：1)通过集中研究资源和基础设施，为专注于症状管理的生物行为临床研究提供研究资源和基础设施，扩大科学家进行护理研究的生物行为研究能力；2)在不同人群中推进包括疲劳及其相关症状在内的症状管理的生物行为方法；3)促进独立的、由研究者发起的具有共同疲劳主题的生物行为研究的开发和扩展；以及4)在症状管理方面建立一个以临床为重点和跨学科性质的可持续生物行为研究的成熟环境。该中心将通过其生物行为科学、生物行为测量和数据服务与分析核心的工作，并通过实施五个受资助的研究项目来实现其目标，这些研究项目研究患有纤维肌痛的女性、乳腺癌女性、孕妇、有心脏代谢风险的女性以及患有镰状细胞疾病的青少年和年轻人的疲劳。该中心将指导当前和不断发展的生物行为科学领域的发展、整合、综合和传播，包括疲劳和相关现象的测量和数据分析方面的进展，并将为更大的生物行为研究社区的科学家提供咨询。

The P30 Center of Excellence for Biobehavioral Approaches to Symptom Management (CEBASM) builds on our successful P20 Exploratory Center for Biobehavioral Clinical Research (CBCR, P20 NR008988, 2004- 2009).The CEBASM will take advantage of the synergy developed via the CBCR related to symptom management and biobehavioral outcomes as well as resources garnered and systems developed for that Center and expand them to advanced application of biobehavioral models, methods, and analyses aimed at understanding biobehavioral mechanisms, interventions, and outcomes related to symptom management with a focus on fatigue. The specific aims of the proposed P30 Center of Excellence are to: 1) expand biobehavioral research capacity for scientists conducting nursing research by centralizing research resources and infrastructure for biobehavioral clinical research focused on symptom management; 2) advance biobehavioral approaches for symptom management, including fatigue and its associated symptoms, in diverse populations; 3) facilitate the development and expansion of biobehavioral programs of independent, investigator-initiated biobehavioral research that have a common theme of fatigue; and 4) establish a mature environment of sustainable biobehavioral research in symptom management that is clinically focused and interdisciplinary in nature. The Center will enact its aims through the work of its cores for Biobehavioral Science, Biobehavioral Measurement, and Data Services and Analysis and through the implementation of five funded research projects studying fatigue in women with fibromyalgia, women with breast cancer, pregnant women, women with cardiometabolic risk, and adolescents and young adults with sickle cell disease. The Center will guide the development, integration, synthesis, and dissemination of current and evolving biobehavioral scientific domains, including advances in measurement and data analysis of fatigue and associated phenomena and will provide consultation to scientists in the larger biobehavioral research community.