Center of Excellence in Biobehavioral Approaches to Symptom Management

P30卓越中心的生物行为方法症状管理（CEBASM）建立在我们成功的P20探索中心的生物行为临床研究（CBCR，P20 NR008988，（2004- 2009年）CEBASM将利用通过CBCR发展的与症状管理和生物行为结果有关的协同作用，以及为该中心收集的资源和开发的系统，将其扩展到生物行为模型，方法和分析的高级应用，旨在了解生物行为机制，干预措施和与症状管理相关的结果，重点是疲劳。拟议的P30卓越中心的具体目标是：1）通过集中研究资源和基础设施，为以症状管理为重点的生物行为临床研究，扩大科学家进行护理研究的生物行为研究能力; 2）推进症状管理的生物行为方法，包括不同人群的疲劳及其相关症状; 3）促进独立的生物行为项目的发展和扩展，由医生发起的生物行为研究具有共同的疲劳主题; 4）建立一个成熟的环境，在症状管理中进行可持续的生物行为研究，这是临床重点和跨学科的性质。该中心将通过其生物行为科学，生物行为测量，数据服务和分析的核心工作，并通过实施五个资助的研究项目，研究纤维肌痛妇女，乳腺癌妇女，孕妇，心脏代谢风险妇女，青少年和年轻人的疲劳制定其目标镰状细胞病。该中心将指导当前和不断发展的生物行为科学领域的发展，整合，综合和传播，包括疲劳和相关现象的测量和数据分析的进展，并将为更大的生物行为研究社区的科学家提供咨询。

The P30 Center of Excellence for Biobehavioral Approaches to Symptom Management (CEBASM) builds on our successful P20 Exploratory Center for Biobehavioral Clinical Research (CBCR, P20 NR008988, 2004- 2009).The CEBASM will take advantage of the synergy developed via the CBCR related to symptom management and biobehavioral outcomes as well as resources garnered and systems developed for that Center and expand them to advanced application of biobehavioral models, methods, and analyses aimed at understanding biobehavioral mechanisms, interventions, and outcomes related to symptom management with a focus on fatigue. The specific aims of the proposed P30 Center of Excellence are to: 1) expand biobehavioral research capacity for scientists conducting nursing research by centralizing research resources and infrastructure for biobehavioral clinical research focused on symptom management; 2) advance biobehavioral approaches for symptom management, including fatigue and its associated symptoms, in diverse populations; 3) facilitate the development and expansion of biobehavioral programs of independent, investigator-initiated biobehavioral research that have a common theme of fatigue; and 4) establish a mature environment of sustainable biobehavioral research in symptom management that is clinically focused and interdisciplinary in nature. The Center will enact its aims through the work of its cores for Biobehavioral Science, Biobehavioral Measurement, and Data Services and Analysis and through the implementation of five funded research projects studying fatigue in women with fibromyalgia, women with breast cancer, pregnant women, women with cardiometabolic risk, and adolescents and young adults with sickle cell disease. The Center will guide the development, integration, synthesis, and dissemination of current and evolving biobehavioral scientific domains, including advances in measurement and data analysis of fatigue and associated phenomena and will provide consultation to scientists in the larger biobehavioral research community.