Optimising the therapeutic efficacy of protein-based drugs against lymph-resident diseases

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Effective treatments for lymphatic diseases (such as HIV and lymph-metastatic cancers) are limited by the lack of drug assess towards the lymphatic sites of disease progression. Improving the access of drugs into lymph therefore has the significant potential to improve the treatment of these illnesses. We will therefore explore a novel approach to improving the lymphatic uptake and retention of protein-based drugs using a useful and widely used biologically compatible polymer.