Structure, Dynamics and Activation Mechanisms of Chemokine Receptors
Structure, Dynamics and Activation Mechanisms of Chemokine Receptors
批准号:
8153252
负责人:
Tracy M Handel
金额:
$88.72万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-30 至 2015-06-30
关键词:
AffinityAnimal ModelBindingBiochemicalBiologicalBiological ProcessBiologyCatalogingCatalogsCell NucleusCellsChicagoCodeCommunitiesComplexContractsCrystallizationDNA biosynthesisDataDiseaseElementsEnsureEnvironmentEnzymesEpigenetic ProcessEventFamilyGene SilencingGenerationsGenetic TranscriptionHistonesHumanIn VitroIndividualLaboratoriesLeadLifeLysineManagement Information SystemsMediatingMethylationMethyltransferaseModificationMolecularMolecular ChaperonesMolecular ConformationMorphologic artifactsOrganismOutcomePatternPerformancePhage DisplayPropertyProtein EngineeringProtein Structure InitiativeProteinsRNA ProcessingReagentRegulationResearchResearch InfrastructureResourcesSet proteinSiteSpecificityStructureStructure-Activity RelationshipSurfaceSystemTailTechnologyTimeUnited States National Institutes of HealthUniversitiesbasecell typecellular imagingchemokine receptorcombinatorialdesignenzyme activityflexibilityhistone methyltransferasehistone modificationin vivoinhibitor/antagonistinterestmeetingsmemberparalogous geneprogramsprotein complexprotein protein interactionreceptorrecombinational repairresearch studysuccess
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依托单位:
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财政年份:2019
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依托单位:
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资助金额:$23.25万
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依托单位:
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Structure Determination of the Chemokine Receptor CCR2 with Novel Inhibitors
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依托单位:
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依托单位:
Dissecting the interactions of gp120 with chemokine receptor CXCR4
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依托单位:
The structural plasticity of chemokine and gp120 recognition by CCR5
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项目类别:
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资助金额:$53.3万
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负责人:Tracy M Handel
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依托单位:
海外基金