NICHD Maternal Fetal Medicine Units Network

NICHD 母胎医学单位网络

• 批准号: 8004987
• 负责人: JORGE ENRIQUE TOLOSA
• 金额: $ 8万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-25 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8004987
• 关键词: Amniotic Fluid; Biological Markers; Cervical; Clinical; Clinical Research; Clinical Trials; Collaborations; Commit; Communities; Consultations; Counseling; Data Quality; Diagnosis; Diagnostic tests; Discipline of obstetrics; Echocardiography; Enrollment; Evidence based practice; Fetal Membranes; Genetic; Gram' s stain; Gynecology; Health; Health Sciences; Histopathology; Hospitals; Immunoassay; Infection; Interleukin-6; Laboratories; Lasers; Mass Spectrum Analysis; Measurement; National Institute of Child Health and Human Development; Oregon; Patient Recruitments; Patients; Pediatric Hospitals; Perinatal; Polymerase Chain Reaction; Pregnancy; Premature Labor; Proteins; Proteomics; Recording of previous events; Reporting; Research; Residencies; Resolution; Services; Site; Specialist; Surface; Time; Ultrasonography; Universities; Vagina; Washington; Woman; Women' s Health; base; experience; fetal; fetal medicine; high risk; intraamniotic infection; maternal serum; microbial; novel; placental membrane; routine Bacterial stain; tandem mass spectrometry

DESCRIPTION (provided by applicant): This application to join the NICHD Maternal Fetal Medicine Units Network is a combined proposal from the Oregon Health & Science University (OHSU) and Kaiser Permanente Oregon/Washington (KPNW) region. It is the result of a long-standing collaboration between OHSU and KPNW in maternal fetal medicine and brings together university and community research capabilities, which will increase diversity in enrollment. The combined deliveries (4091 in 2003 and 4043 in 2004) concentrate high risk patients in principally two sites: the Perinatal Center at Doernbecher Children's hospital at OHSU and the KPNW Perinatal Center at St. Vincent's Hospital. Both centers serve to selectively funnel consultations for genetics, preconception counseling, high resolution ultrasonography, high risk obstetrics and fetal echocardiography and are staffed by Maternal Fetal Medicine Specialists. Both OHSU and KPNW have a long history of conducting respected clinical research independently and together. This collaboration is based upon shared laboratory services and maternal fetal medicine coverage, an integrated residency in Obstetrics & Gynecology, and the combined strengths in research of the KPNW Center for Health Research and the Oregon Evidence-based Practice Center. The Center for Health Research (KPNW) and the Women's Health Research Unit (OHSU) have extensive experience in clinical trials and the research staff to facilitate the enrollment of patients in clinical studies. Focusing patient recruitment in two sites staffed by maternal fetal medicine specialists committed to this proposal will enhance enrollment and participation by research staff as well as maximize the quality of data obtained.

描述（由申请人提供）：本申请加入NICHD产妇胎儿医学单位网络是一个联合提案，由俄勒冈州健康与科学大学（OHSU）和凯撒永久俄勒冈州/华盛顿（KPNW）地区。这是OHSU和KPNW在母胎医学方面长期合作的结果，汇集了大学和社区的研究能力，这将增加招生的多样性。合并分娩（2003年4 091人，2004年4 043人）主要集中在两个地点：OHSU Doernbecher儿童医院围产期中心和圣文森特医院KPNW围产期中心。这两个中心都有选择性地为遗传学、孕前咨询、高分辨率超声检查、高风险产科和胎儿超声心动图提供咨询，并配备了产妇胎儿医学专家。OHSU和KPNW都有独立和共同进行受人尊敬的临床研究的悠久历史。这种合作是基于共享的实验室服务和孕产妇胎儿医学覆盖范围，在妇产科综合住院医师，以及在KPNW中心的健康研究和俄勒冈州循证实践中心的研究的综合优势。健康研究中心（KPNW）和妇女健康研究单位（OHSU）在临床试验和研究人员方面具有丰富的经验，可促进患者入组临床研究。将患者招募集中在两个由致力于这一提议的母胎医学专家组成的研究中心，将提高研究人员的招募和参与，并最大限度地提高所获得数据的质量。