NICHD Maternal Fetal Medicine Units Network

描述（由申请人提供）：本申请加入NICHD母胎医学单位网络是俄勒冈健康与科学大学（OHSU）和凯撒医疗机构俄勒冈/华盛顿（KPNW）地区的联合提议。这是OHSU和KPNW在母胎医学方面长期合作的结果，并汇集了大学和社区的研究能力，这将增加招生的多样性。合并分娩（2003年为4091例，2004年为4043例）主要将高危患者集中在两个地点：OHSU Doernbecher儿童医院的围产期中心和圣文森特医院KPNW围产期中心。这两个中心都有选择性地为遗传学、孕前咨询、高分辨率超声检查、高风险产科和胎儿超声心动图提供咨询，并由母胎医学专家组成。OHSU和KPNW在独立和共同开展受人尊敬的临床研究方面有着悠久的历史。这项合作的基础是共享实验室服务和母婴医学覆盖范围，妇产科综合住院医师，以及KPNW健康研究中心和俄勒冈循证实践中心在研究方面的综合优势。健康研究中心（KPNW）和妇女健康研究单位（OHSU）在临床试验和研究人员方面拥有丰富的经验，以促进临床研究中患者的登记。将患者招募重点放在两个由致力于本提案的母胎医学专家组成的地点，将加强研究人员的招募和参与，并最大限度地提高所获得数据的质量。

DESCRIPTION (provided by applicant): This application to join the NICHD Maternal Fetal Medicine Units Network is a combined proposal from the Oregon Health & Science University (OHSU) and Kaiser Permanente Oregon/Washington (KPNW) region. It is the result of a long-standing collaboration between OHSU and KPNW in maternal fetal medicine and brings together university and community research capabilities, which will increase diversity in enrollment. The combined deliveries (4091 in 2003 and 4043 in 2004) concentrate high risk patients in principally two sites: the Perinatal Center at Doernbecher Children's hospital at OHSU and the KPNW Perinatal Center at St. Vincent's Hospital. Both centers serve to selectively funnel consultations for genetics, preconception counseling, high resolution ultrasonography, high risk obstetrics and fetal echocardiography and are staffed by Maternal Fetal Medicine Specialists. Both OHSU and KPNW have a long history of conducting respected clinical research independently and together. This collaboration is based upon shared laboratory services and maternal fetal medicine coverage, an integrated residency in Obstetrics & Gynecology, and the combined strengths in research of the KPNW Center for Health Research and the Oregon Evidence-based Practice Center. The Center for Health Research (KPNW) and the Women's Health Research Unit (OHSU) have extensive experience in clinical trials and the research staff to facilitate the enrollment of patients in clinical studies. Focusing patient recruitment in two sites staffed by maternal fetal medicine specialists committed to this proposal will enhance enrollment and participation by research staff as well as maximize the quality of data obtained.