Operation of an Animal Diagnostic Laboratory

动物诊断实验室的运营

• 批准号: 8036362
• 负责人: CYNTHIA L. BESCH-WILLIFORD
• 金额: $ 4.5万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2010-12-01
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8036362
• 关键词: Acquired Immunodeficiency Syndrome; Animals; Contracts; Diagnostic; Health; Health Status; Laboratories; Laboratory Animals; Malignant Neoplasms; Molecular; Monitor; National Cancer Institute; Pathologic; Production; Research Personnel; Rodent; Serologic tests; Services; Testing; in vivo; operation; pathogen; programs

A part of the search for active agents against Cancer and AIDS involves in vivo testing. The National Cancer Institute (NCI) maintains the Animal Production Program to supply the necessary laboratory animals needed for this in vivo testing. Much of the testing is performed in pathogen-free laboratory animals such as the ones produced by the Animal Production Program contract colonies. Thus, a health monitoring contract is used to determine the health status of the Animal Production Program rodent colonies. The determination of the health status of the NCI Animal Production Program contract rodent colonies is the primary objective of this effort. This effort is accomplished by utilizing tests for serologic, bacteriologic, parasitological, pathologic and molecular services.

寻找抗癌症和艾滋病的活性剂的一部分涉及体内测试。美国国家癌症研究所（NCI）维持动物生产计划，以提供该体内试验所需的必要实验室动物。大部分测试是在无病原体的实验室动物中进行的，例如动物生产计划合同殖民地生产的动物。因此，健康监测合同用于确定动物生产计划啮齿动物群落的健康状况。确定NCI动物生产计划合同啮齿动物群的健康状况是这项工作的主要目标。这项工作是通过利用血清学、细菌学、寄生虫学、病理学和分子学服务的测试来完成的。