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Lung-Liver Axis During Pneumonia

Lung-Liver Axis During Pneumonia
肺炎期间的肺肝轴
批准号：
8076424
负责人：
Lee Quinton
金额：
$24.9万
依托单位：
BOSTON UNIVERSITY MEDICAL CAMPUS
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-09-01 至 2013-06-30
来源：
https://reporter.nih.gov/project-details/8076424
关键词：
AccountingAcute Lung InjuryAcute-Phase ProteinsAcute-Phase ReactionAddressAlveolarAmyloidApoptoticBacterial PneumoniaBindingBiologicalBiological MarkersBiological ProcessBloodC-reactive proteinCell LineCellsCessation of lifeChemotaxisComplementCytokine SignalingDataDisease ProgressionEdemaEnvironmentEscherichiaEscherichia coliGene DeletionGene ExpressionGenesGoalsHepaticHepatocyteHost DefenseImmune responseIn VitroIndividualInfectionInfection preventionInflammationInflammatoryInflammatory ResponseInterleukin-1Interleukin-6LaboratoriesLiverLower respiratory tract structureLungMeasuresMediatingMediator of activation proteinMentorsMessenger RNAMusNF-kappa BNatural ImmunityNeutrophil InfiltrationOutcomePatientsPhagocytosisPhasePlasmaPlasma ProteinsPneumoniaPreventionProtein BindingProteinsPublic Health SchoolsReceptor SignalingRecombinant CytokinesResearchRoleSTAT3 geneSerumSerum amyloid A proteinSignal PathwaySignal TransductionSmall Interfering RNAStat3 proteinStreptococcus pneumoniaeSystemTestingTranscriptional RegulationTumor Necrosis Factor ReceptorTumor Necrosis Factor-alphaTumor Necrosis Factorsbaseburden of illnesscareercareer developmentchromatin immunoprecipitationcytokinein vivoinnovationknock-downleukocyte activationlipopolysaccharide-binding proteinloss of functionlung injurymicrobialneutralizing antibodynew therapeutic targetnovel strategiesprogramspromoterprotein expressionresponsetooltranscription factor

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