CMV meeting support

CMV 会议支持

• 批准号: 8130117
• 负责人: TIMOTHY F KOWALIK
• 金额: $ 0.8万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-15 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8130117
• 关键词: Academia; Acquired Immunodeficiency Syndrome; Animals; Award; Child; Clinic; Clinical; Clinical Sciences; Congenital Abnormality; Cytomegalovirus; Development; Disease; Educational workshop; Exanthema Subitum; Faculty; Fees; Fever; Funding; Germany; Goals; Grant; Herpesviridae; Human; Human Herpesvirus 6; Human Herpesvirus 7; Immunocompromised Host; Industry; Infection; Infectious Agent; International; Laboratories; Malignant Neoplasms; Medical Students; Morbidity - disease rate; Multiple Sclerosis; Museums; Neurodegenerative Disorders; Organ; Patients; Peer Review; Postdoctoral Fellow; Research; Research Personnel; Role; Scientist; Tissues; Transplant Recipients; Travel; Vaccines; Virus; Virus Diseases; Work; abstracting; base; graduate student; improved; meetings; mortality; posters; professor; symposium; therapy development; virology

DESCRIPTION (provided by applicant): The 2-herpesvirus subfamily is composed of viruses found ubiquitously in humans and other animals. The cause lifelong infections and are associated with debilitating diseases, including certain cancers, in humans. Human cytomegalovirus (CMV) is a major cause of morbidity and mortality in immunosuppressed patients, including organ and tissue transplant recipients, and AIDS patients. Moreover, CMV is the leading cause of birth defects associated with an infectious agent. HHV6 causes roseola infantum, a febrile illness of children and mounting evidence suggests that HHV6 contributes to organ rejection in transplant patients and may exacerbate neurodegenerative disorders such as multiple sclerosis. Significant effort in academia, the clinic and industry is being devoted to improve therapies and develop effective vaccines against these viruses. The 13th International Cytomegalovirus and 2- Herpesvirus Workshop is the only meeting of academic and industrial scientists, and clinicians to share discoveries in basic virology and clinical science with the goal of improving the management of infections by these viruses. PUBLIC HEALTH RELEVANCE: Cytomegalovirus (CMV) is a major cause of morbidity and mortality in immunosuppressed patients including organ and tissue transplant recipients and AIDS patients. Moreover, CMV is the leading cause of birth defects associated with an infectious agent and mounting evidence suggests a possible role for CMV in certain cancers. HHV6 causes roseola infantum, a febrile illness of children and mounting evidence suggests that HHV6 contributes to organ rejection in transplant patients and may exacerbate neurodegenerative disorders such as multiple sclerosis. The 13th International Cytomegalovirus and 2- Herpesvirus Workshop is the premier meeting of scientists and clinicians to share discoveries in basic virology and clinical science with the goal of improving the management of infections by these viruses.

描述(申请人提供)：2-疱疹病毒亚家族由在人类和其他动物中普遍存在的病毒组成。它会导致终生感染，并与人体内包括某些癌症在内的衰弱疾病有关。人类巨细胞病毒(CMV)是免疫抑制患者，包括器官和组织移植受者以及艾滋病患者的主要致病和死亡原因。此外，巨细胞病毒是与感染性病原体有关的出生缺陷的主要原因。HHV6会导致婴儿红疹，这是一种儿童发热性疾病，越来越多的证据表明，HHV6会导致移植患者的器官排斥反应，并可能加剧多发性硬化症等神经退行性疾病。学术界、临床和产业界正在致力于改进治疗方法和开发针对这些病毒的有效疫苗。第13届国际巨细胞病毒和2-疱疹病毒研讨会是学术和工业科学家以及临床医生分享基础病毒学和临床科学发现的唯一会议，目的是改善对这些病毒感染的管理。 公共卫生相关性：巨细胞病毒(CMV)是免疫抑制患者(包括器官和组织移植受者以及艾滋病患者)发病率和死亡率的主要原因。此外，巨细胞病毒是与感染性病原体相关的出生缺陷的主要原因，越来越多的证据表明巨细胞病毒在某些癌症中可能发挥作用。HHV6会导致婴儿红疹，这是一种儿童发热性疾病，越来越多的证据表明，HHV6会导致移植患者的器官排斥反应，并可能加剧多发性硬化症等神经退行性疾病。第13届国际巨细胞病毒和2-疱疹病毒研讨会是科学家和临床医生分享基础病毒学和临床科学发现的主要会议，目的是改善对这些病毒感染的管理。