Research Training Program in Gastroenterology

胃肠病学研究培训计划

• 批准号: 8052895
• 负责人: Jack R Wands
• 金额: $ 12.68万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8052895
• 关键词: Gastroenterology; Research Training; Training Programs

DESCRIPTION (provided by applicant): The major thrust of this Gastroenterology Research Training Program is to prepare the M.D., Ph.D, M.D./Ph.D., post-doctoral fellow, and pre-doctoral student for a career as a physician/scientist and/or independent investigator in academic Gastroenterology. There are eight multi-faceted faculty to provide prospective trainees opportunities in contemporary approaches to cellular/molecular biology, oncogenesis, signal transduction pathways, virology, immunology, stem cell biology, and biochemistry. Faculty have been recruited from the Department(s) of Medicine, and Pediatrics, and from the Brown University Pathobiology and the Molecular and Cellular Biology (MCB) Program and all operate well-funded research programs (approximately $4.8 million annual direct costs). In this context, there is a major effort to provide opportunities in translational research at the Liver Research Center and Rhode Island Hospital. In these facilities, there is access to quantitative imaging, laser capture micro-dissection, genomics and proteomics, flow cytometry, transgenic animals, and human tissue banks. The pre-doctoral trainees are recruited from the Pathobiology and MCB Graduate Program(s), and enter with majors in biology, chemistry, and cell biology. These students have a commitment to basic research on the mechanisms of human disease. The Post-doctoral trainees are recruited from several sources including the graduate programs at Brown and elsewhere as well as those having completed the minimum of two years in the Brown University/Affiliated Hospital Clinical Adult and Pediatric Gastroenterology Fellowship Program. We request two postdoctoral M.D., M.D., Ph.D. or Ph.D. trainees who will devote two or three years to basic or translational research. The research effort will be 90% for M.D. or M.D./Ph.D, and 100% for Ph.D post-doctoral Fellows. There is a request for two pre-doctoral trainees enrolled in the M.D., M.D./Ph.D. or Ph.D. graduate programs at Brown University. The trainees are instructed in the responsible conduct of research and have the opportunity to develop communication and teaching skills during the training program. Both pre- and post-doctoral trainees are required to participate in didactic courses that are enriched by weekly research seminars, journal clubs, career development workshops, and symposia. There is a strong mentoring program to develop skills in communication, grantsmanship, interdisciplinary interactions, and the implementation of basic research approaches for the diagnosis and prevention of gastrointestinal diseases. The training program is committed to offering opportunities to minority pre- and postdoctoral trainees, and there is a robust program to recruit underrepresented minority candidates. Thus the Brown University/Lifespan Affiliated Hospital Program is designed to develop academic careers in Gastroenterology and Hepatology. PUBLIC HEALTH RELEVANCE: This grant is a Training Program for diseases of the gastrointestinal tract and liver. Trainees are comprised of pre-doctoral and post-doctoral candidates with the MD, PhD, or both degrees. A major emphasis of the program is to train biomedical scientist and physician scientist using state of the art investigative techniques.

描述(由申请人提供)： 胃肠病学研究培训计划的主要目的是为医学博士、博士、医学博士/博士、博士后研究员和博士后学生在学术胃肠病学领域作为医生/科学家和/或独立研究员的职业生涯做准备。有八个多方面的学院，为未来的受训人员提供当代细胞/分子生物学、肿瘤发生、信号转导途径、病毒学、免疫学、干细胞生物学和生物化学的机会。教员来自(S)医学系和儿科学系，以及布朗大学病理生物学和分子与细胞生物学(MCB)计划，所有这些都运作着资金充足的研究项目(每年直接成本约为480万美元)。在这种情况下，肝脏研究中心和罗德岛医院正在努力提供翻译研究的机会。在这些设施中，可以获得定量成像、激光捕获显微解剖、基因组学和蛋白质组学、流式细胞术、转基因动物和人类组织库。博士前实习生来自病理生物学和微生物学研究生项目(S)，并以生物、化学和细胞生物学专业录取。这些学生致力于人类疾病机制的基础研究。博士后实习生从几个来源招募，包括布朗大学和其他地方的研究生课程，以及那些在布朗大学/附属医院临床成人和儿科胃肠病奖学金计划中至少完成两年的学生。我们需要两名博士后医学博士、医学博士、博士或博士后实习生，他们将花费两到三年的时间从事基础或翻译研究。医学博士或医学博士/博士研究生的研究努力将达到90%，博士后研究员的研究将达到100%。有两名博士前实习生申请在布朗大学攻读医学博士、医学博士或博士研究生课程。受训者接受负责任的研究指导，并有机会在培训期间发展沟通和教学技能。博士后和博士后实习生都需要参加教学课程，这些课程包括每周的研究研讨会、期刊俱乐部、职业发展研讨会和研讨会。有一个强大的指导计划，以培养沟通、专业技能、跨学科互动以及实施诊断和预防胃肠道疾病的基本研究方法方面的技能。该培训计划致力于为少数族裔博士后和博士后实习生提供机会，并有一个强有力的计划来招募代表性不足的少数族裔候选人。因此，布朗大学/LIFESPAN附属医院项目旨在发展胃肠病学和肝脏病学的学术事业。 公共卫生相关性：这笔赠款是针对胃肠道和肝脏疾病的培训计划。实习生由拥有医学博士学位和/或博士学位的博士后和博士后候选人组成。该计划的一个主要重点是使用最先进的调查技术培训生物医学科学家和内科科学家。