Epidemiology, Clinical Trials adn Outcomes Research in Nephrology

肾脏病学的流行病学、临床试验和结果研究

• 批准号: 8098832
• 负责人: ANDREW S LEVEY
• 金额: $ 9.52万
• 依托单位: TUFTS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-20 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8098832
• 关键词: Clinical Trials; Epidemiology; Nephrology; Outcomes Research

DESCRIPTION (provided by applicant): Chronic kidney disease (CKD) is a public health problem in the US. Reports from the National Institutes of Health and Institute of Medicine recommend strengthening training programs for physicians in the methods of clinical research to translate advances in basic science to improvements in health. This application is to renew the training program in "Epidemiology, Clinical Trials and Outcomes Research" established ten years ago within the William B. Schwartz Division of Nephrology at Tufts Medical Center and Tufts University School of Medicine. Andrew S. Levey, MD and Mark J. Sarnak, MD, MS remain the Program Director and Associate Program Director, respectively. The proposed training program is unique in that it combines training by nephrologists with outstanding records in cutting-edge clinical research and by established scientists in epidemiology, biostatistics and health services research. Faculty supervision is complemented by oversight by internal and external advisors, including senior clinical investigators and world leaders in public health related to CKD. The specific aims are unchanged but their execution has been substantially strengthened by growth and maturation of research in the Division of Nephrology and the creation of the Tufts Clinical and Translational Sciences Institute, funded by the NIH: 1) Didactic Training - course work in fulfillment of the MS degree in the Graduate Program in Clinical Research at the Sackler School of Graduate Biomedical Sciences at Tufts University, with 3 new areas of concentration. 2) Independent Study - an hypothesis-based research project supervised by a nephrologist mentor and a research team of faculty with expertise in other disciplines. Nephrology faculty and their collaborators have databases and ongoing studies that can serve as the subject of the trainees' research projects, now including acute kidney injury and genetic epidemiology. 3) Training in Presentation and Publication - participation in conferences and seminars designed to improve trainees' oral and written presentations, now including experience in medical editing. Integration of all aspects of the curriculum with trainees' research projects is ensured by the nephrologist mentors. All 16 approved trainee positions in the past 4 years have been filled. An additional 14 trainee positions have been supported by other sources during this time. For 2009, 4 approved slots have also been filled; 85 applications were received for the 2 new positions. Of the 41 trainees who have completed the program since its inception, 26 have remained in academic medicine, 5 are in industry or government, and 9 have entered clinical practice and 1 is still in his clinical fellowship. Renewal of 4 training positions per year is requested for the next 5 years. PUBLIC HEALTH RELEVANCE: Chronic kidney disease (CKD) is a public health problem in the US. Training physicians in methods of clinical research is necessary to translate advances in science to improve health of people with CKD. Our training program is designed to train physicians in research on CKD and has a track record of success.

描述（由申请人提供）：慢性肾脏病（CKD）是美国的一个公共卫生问题。美国国立卫生研究院和医学研究所的报告建议加强对医生的临床研究方法培训计划，以将基础科学的进步转化为健康的改善。本申请是为了更新十年前在威廉B内建立的“流行病学、临床试验和结果研究”培训项目。塔夫茨医学中心和塔夫茨大学医学院的Schwartz肾脏病学分部。Andrew S. Levey，MD和Mark J. Sarnak，MD，MS分别担任项目总监和副项目总监。拟议的培训计划是独一无二的，因为它结合了肾脏病学家在尖端临床研究和流行病学，生物统计学和卫生服务研究方面的杰出记录的培训。教师监督由内部和外部顾问监督补充，包括高级临床研究人员和与CKD相关的公共卫生领域的世界领导者。 具体目标没有改变，但其执行已大大加强了肾脏科研究的增长和成熟，并建立了塔夫茨临床和转化科学研究所，由NIH资助：1）教学培训-塔夫茨大学萨克勒生物医学研究生院临床研究生课程硕士学位的课程工作，三个新的集中领域。2)独立研究-一个基于假设的研究项目，由肾病学家导师和具有其他学科专业知识的教师研究团队监督。肾脏病学教师和他们的合作者有数据库和正在进行的研究，可以作为学员研究项目的主题，现在包括急性肾损伤和遗传流行病学。3)演讲和出版培训-参加旨在提高学员口头和书面演讲的会议和研讨会，现在包括医学编辑经验。课程的各个方面与学员的研究项目的整合是由肾病学家导师确保的。 过去4年批准的16个实习生职位均已填补。在此期间，另有14个受训人员职位得到其他来源的支助。2009年，4个核定空缺也已填补; 2个新职位收到85份申请。在自成立以来完成该计划的41名学员中，26人留在学术医学领域，5人在工业或政府部门，9人进入临床实践，1人仍在临床研究金。要求在今后5年中每年更新4个培训职位。 公共卫生相关性：慢性肾脏病（CKD）是美国的一个公共卫生问题。对医生进行临床研究方法的培训是将科学进步转化为改善CKD患者健康的必要条件。我们的培训计划旨在培训CKD研究方面的医生，并有成功的记录。