Pre-clinical Safety and Efficacy of Reversed Chloroquines

反向氯喹的临床前安全性和有效性

• 批准号: 8144570
• 负责人: DAVID H PEYTON
• 金额: $ 62.45万
• 依托单位: PORTLAND STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-23 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8144570
• 关键词: Address; Adverse effects; Animal Testing; Antimalarials; Applications Grants; Award; Chemical Agents; Chemicals; Child; Chloroquine; Chloroquine resistance; Clinical Research; Clinical Trials; Combined Modality Therapy; Contractor; Contracts; Development; Disease; Dose; Drug Design; Drug Kinetics; Drug resistance; Evaluation; Funding; Future; Goals; Gold; Grant; Health; Health Sciences; Human; In Vitro; Individual; Institution; International; Investigational Drugs; Laboratories; Lead; Link; Malaria; Molecular; Monkeys; Mus; Oregon; Parasites; Pharmaceutical Preparations; Pharmacodynamics; Pharmacology; Phase; Plasmodium falciparum; Predisposition; Pregnant Women; Procedures; Rattus; Research; Research Contracts; Resistance; Safety; Small Business Technology Transfer Research; Staging; Structure-Activity Relationship; Testing; Therapeutic Index; Toxic effect; United States Food and Drug Administration; Universities; Vacuole; Work; chemosensitizing agent; chemotherapy; cost; cytotoxicity; design; drug candidate; falls; fitness; flexibility; in vivo; killings; meetings; novel; pre-clinical; preclinical evaluation; preclinical study; resistant strain; single molecule