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Role of PKA in autoimmune diabetes through dendritic cells (DC) and regulatory T

Role of PKA in autoimmune diabetes through dendritic cells (DC) and regulatory T
PKA 通过树突状细胞 (DC) 和调节性 T 在自身免疫性糖尿病中的作用
批准号：
8125445
负责人：
Hua Gu
金额：
$40.21万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-09-01 至 2011-08-31
来源：
https://reporter.nih.gov/project-details/8125445
关键词：
AblationAdoptive TransferAffectAntigensAutoantigensAutoimmune DiabetesAutoimmune DiseasesAutoimmunityBiological ModelsCD28 geneCD4 Positive T LymphocytesCD80 geneCell physiologyCellsCyclic AMP-Dependent Protein KinasesDataDendritic CellsDevelopmentDiabetes MellitusDiabetic mouseExhibitsFoundationsGoalsHomeostasisImmuneImmune responseInbred NOD MiceIndividualInsulin-Dependent Diabetes MellitusInterleukin-10Interleukin-2LeadLymphoidMediatingMolecularMouse StrainsMusMutationNF-kappa BOrganPathway interactionsPeripheralPhenotypePlayPreventionReagentRegimenRegulationRegulatory T-LymphocyteReportingRoleSignal TransductionSupporting CellT-LymphocyteTestingTherapeuticTherapeutic EffectThymus GlandTransgenic MiceVitamin DVitamin D3 Receptorautoreactive T cellbasecytokinein vitro Assayinsightmutantp65preventpublic health relevance

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