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Target Mycobacterium Protein Tyrosine Phosphatase B for Anti-Tuberculosis Agents

Target Mycobacterium Protein Tyrosine Phosphatase B for Anti-Tuberculosis Agents
用于抗结核药物的靶分枝杆菌蛋白酪氨酸磷酸酶 B
批准号：
8089759
负责人：
Zhong-Yin Zhang
金额：
$40.65万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-07-26 至 2012-06-30
来源：
https://reporter.nih.gov/project-details/8089759
关键词：
Action PotentialsActive SitesAdverse effectsAffectAffinityAnimal ModelAnimalsAntibioticsAntimycobacterial AgentsAntitubercular AgentsApoptosisBindingCell AdhesionCell WallCell membraneCell physiologyCessation of lifeCombinatorial SynthesisCommunicable DiseasesComplexCytoplasmCytosolDevelopmentDiabetes MellitusDrug Delivery SystemsDrug Resistant TuberculosisEffectivenessEnergy MetabolismEnzymesEtiologyEvaluationEventExtreme drug resistant tuberculosisFamilyGenus MycobacteriumGoalsHumanImmune System DiseasesImmune responseInfectionInterdisciplinary StudyLaboratoriesLeadLibrariesLinkMalignant NeoplasmsMediatingMetabolismMicrobeMolecularMulti-Drug ResistanceMultidrug-Resistant TuberculosisMycobacterium tuberculosisNaturePathogenesisPhagocytosisPharmaceutical PreparationsPhosphoric Monoester HydrolasesPhosphotyrosinePhylogenetic AnalysisPlayPopulationPost-Translational Protein ProcessingProtein Tyrosine KinaseProtein Tyrosine PhosphataseProteinsProteomicsPublic HealthRNARegulationResearchResistanceRoentgen RaysRoleSalicylic AcidsSalmonellaSignal PathwaySignal TransductionStructureTherapeuticTreatment ProtocolsTuberculosisTyrosine PhosphorylationVirulence FactorsVirusYersiniaYersinia yopH proteinabstractingbactericidebasecell growthcombatcompliance behaviordesignhigh throughput screeninghuman diseaseimprovedin vivoinhibitor/antagonistinnovationinorganic phosphateinterestmacrophagemigrationmultidisciplinarymycobacterialnew therapeutic targetnovelnovel therapeuticspre-clinicalprogramssmall moleculetooltuberculosis treatmentweapons

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  • 批准号：
    10113552
  • 项目类别：
  • 资助金额：
    $42.9万
  • 财政年份：
    2017
  • 负责人：
    Zhong-Yin Zhang
  • 依托单位：
    PURDUE UNIVERSITY
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