Evaluating the in vivo Efficacy of CD4i Antibody, m9
Evaluating the in vivo Efficacy of CD4i Antibody, m9
批准号:
8103377
负责人:
Antony S. Dimitrov
金额:
$62.57万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-07-08 至 2012-06-30
关键词:
AlbuminsAnimalsAntibodiesAntibody FormationAntiviral AgentsBindingBiological AssayCCR5 geneCXCR4 geneCell LineCell SizeCellsChinese Hamster Ovary CellControl GroupsDevelopmentDoseDropsDrug KineticsEmploymentEngineeringEpitopesExposure toFc ReceptorGlycoproteinsGoalsHIVHIV Envelope Protein gp120HIV vaccineHIV-1HumanIgG1Immune responseImmunoglobulin FragmentsImmunoglobulin GIn VitroInfectionInfection ControlIntramuscular InjectionsMacacaMacaca mulattaMediatingModificationMonkeysOutsourcingProductionPropertyProphylactic treatmentProteinsRoleSolutionsSpottingsTestingVaccinesVariantViralViral Load resultVirusbasechemokine receptorhydroxy-aluminum polymerimprovedin vivointerestneutralizing antibodyprotective efficacyprotein aminoacid sequenceprotein structurepublic health relevancereceptor bindingrectalresponsesuccesstherapeutic targettransmission processvaccine development
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