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The Influence of Anti-N-Acetyl-D-Glucosamine B cells on Type One Diabetes in Mice

The Influence of Anti-N-Acetyl-D-Glucosamine B cells on Type One Diabetes in Mice
抗N-乙酰-D-葡萄糖胺B细胞对小鼠一型糖尿病的影响
批准号：
8075993
负责人：
John Franklin Kearney
金额：
$36.63万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-07-01 至 2011-06-30
来源：
https://reporter.nih.gov/project-details/8075993
关键词：
AcetylglucosamineAntibodiesAntibody FormationAntigen PresentationApoptosisAsthmaAutoimmune DiabetesAutoimmune DiseasesAutoimmune ProcessAutoimmune ResponsesB-Lymphocyte SubsetsB-LymphocytesBacteriaBindingBirthBlocking AntibodiesBlood GlucoseBlood VesselsCD4 Positive T LymphocytesCD8B1 geneCarbohydratesCell DeathCell SeparationCell WallCell physiologyCellsChildhoodChitinCommunicable DiseasesDataDefectDevelopmentDiabetes MellitusDiagnosisDiseaseEnzymesEpidemiologic StudiesEpitopesEventFamilyFrequenciesGeneticGlucosamineGoalsHumanImmuneImmune systemImmunizationImmunofluorescence ImmunologicIn SituInbred NOD MiceIncidenceIndividualInfectionInfectious AgentInsulinInsulin-Dependent Diabetes MellitusIslets of LangerhansKnowledgeLifeLymphocyteMammalian CellMediatingModelingModificationMonitorMouse StrainsMusN-terminalNecrosisNeonatalNeurologicNon obeseOrganismPancreasPhenotypePolymersPopulationPreventionPrevention strategyProcessProtein DynamicsProteinsResistanceRodent ModelRoleSSCP AnalysisScarlet FeverSeveritiesSimulateSocietiesSpecificityStagingStreptococcal InfectionsStreptococcal VaccinesStreptococcus pyogenesStressT-LymphocyteT-Lymphocyte EpitopesTestingTimeTo autoantigenTransgenic MiceVaccinationabstractingautoreactive T cellbaseblood glucose regulationcritical perioddiabetichumoral immunity deficiencyimprovedisletlymph nodesmouse developmentmouse modelpreventprotective effecttherapy development

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期刊论文(1)
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会议论文
Manipulation of the glycan-specific natural antibody repertoire for immunotherapy.
DOI： 10.1111/imr.12397
发表时间： 2016-03
期刊： Immunological reviews
影响因子： 8.7
作者： [New JS, King RG, Kearney JF]
通讯作者： Kearney JF
Development and maintenance of human glycan and phospholipid antibody repertoires
Development and maintenance of human glycan and phospholipid antibody repertoires
Antibody induction by Group B streptococcal vaccines for protection against fungal infections
Effects of neonatal microbial exposure on anti-polysaccharide B cell development
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