Mitigation of Radiation Pneumonopathy By Lignan Action

通过木酚素作用缓解放射性肺炎

• 批准号: 7586002
• 负责人: Melpo Christofidou-Solomidou
• 金额: $ 100万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7586002
• 关键词: Acute; Adverse effects; Anti-Inflammatory Agents; Anti-inflammatory; Antioxidants; Apoptosis; Arts; Canada; Cell Cycle; Chest; China; Chronic; Clinic; Clinical; Clinical Trials; Complex; Data; Denmark; Diet; Dietary Fiber; Dose; Enzymes; Exploratory/Developmental Grant for Diagnostic Cancer Imaging; Explosion; Exposure to; Fibrosis; Flax; Generations; Genes; Goals; Image; Injury; Ionizing radiation; Life; Lignans; Longitudinal Studies; Lung; Lung Inflammation; Mediating; Mediator of activation protein; Methodology; Modeling; Mus; Oxidative Stress; Pathway interactions; Patients; Phase; Plants; Pneumonia; Positron-Emission Tomography; Production; Property; Radiation; Radiation Injuries; Reactive Oxygen Species; Reperfusion Injury; Rodent; Role; Structure of parenchyma of lung; Tablets; Therapeutic; Time; Tissues; Toxic effect; Translations; Transplantation; Work; X-Ray Computed Tomography; abstracting; cytotoxic; dirty bomb; flaxseed lignan; human TGFB1 protein; internal radiation; lung injury; lung ischemia; mouse model; novel; novel therapeutics; pre-clinical; response; secoisolariciresinol diglucoside

项目成果

Oxidative Lung Damage Resulting from Repeated Exposure to Radiation and Hyperoxia Associated with Space Exploration.

与太空探索相关的反复暴露于辐射和高氧血症导致的氧化性肺损伤。

• 发表时间: 2013
• 期刊: Journal of pulmonary & respiratory medicine
• 作者: Pietrofesa,RalphA;Turowski,JasonB;Arguiri,Evguenia;Milovanova,TatyanaN;Solomides,CharalambosC;Thom,StephenR;Christofidou-Solomidou,Melpo
• 通讯作者: Christofidou-Solomidou,Melpo