Markers and therapeutic strategies for overcoming chemoradiotherapy resistance
克服放化疗耐药性的标志物和治疗策略
基本信息
- 批准号:8332452
- 负责人:
- 金额:$ 29.05万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-09-26 至 2016-07-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAntibodiesCandidate Disease GeneCetuximabCisplatinClinicalCollaborationsDNA Repair PathwayDataData SetDatabasesDiseaseDistant MetastasisDistressDouble Strand Break RepairEpidermal Growth Factor ReceptorEpidermal Growth Factor Receptor Tyrosine Kinase InhibitorFormalinFundingGene ExpressionGene Expression ProfileGrantHead and Neck Squamous Cell CarcinomaHuman PapillomavirusImmunohistochemistryIn VitroIndividualInstructionLungMalignant Epithelial CellMesenchymalMeta-AnalysisOutcomeParaffin EmbeddingPathway interactionsPatientsPhasePhase III Clinical TrialsPhysiciansPopulationPostoperative PeriodPrognostic MarkerProteinsProteomicsRadiation Therapy Oncology GroupRandomizedRegimenRelapseResearch PersonnelResistanceSignal PathwaySignal TransductionSocietiesSourceSpecialized Program of Research ExcellenceSpecimenTelomeraseTestingTherapeuticTissuesToxic effectValidationXRCC5 genebasecandidate markerclinical applicationclinical practicecombatdesignepithelial to mesenchymal transitionexperiencegenome-wideimprovedin vitro Modelnovelnovel markerpre-clinicalpreferenceprogramsrandomized trialreceptor expressionresistance mechanismresponseresponse markertherapeutic targettumorworking group
项目摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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John V. Heymach其他文献
Molecular targets for cancer chemoprevention
癌症化学预防的分子靶点
- DOI:
10.1038/nrd2663 - 发表时间:
2009-03-01 - 期刊:
- 影响因子:101.800
- 作者:
William N. William;John V. Heymach;Edward S. Kim;Scott M. Lippman - 通讯作者:
Scott M. Lippman
Impact of co-mutations on the immune microenvironment of KRAS-mutant lung adenocarcinoma
- DOI:
10.1016/j.jtho.2015.12.021 - 发表时间:
2016-02-01 - 期刊:
- 影响因子:
- 作者:
Ferdinandos Skoulidis;Warren Denning;Lixia Diao;Pan Tong;You Hong Fan;Vassiliki Papadimitrakopoulou;Julie Izzo;Carmen Behrens;Humam Kadara;Edwin R. Parra Cuentas;Jaime Rodriguez Canales;Jing Wang;Lauren A. Byers;Ignacio I. Wistuba;John V. Heymach - 通讯作者:
John V. Heymach
Progress and challenges of artificial intelligence in lung cancer clinical translation
人工智能在肺癌临床转化中的进展与挑战
- DOI:
10.1038/s41698-025-00986-7 - 发表时间:
2025-07-01 - 期刊:
- 影响因子:8.000
- 作者:
Erjia Zhu;Amgad Muneer;Jianjun Zhang;Yang Xia;Xiaomeng Li;Caicun Zhou;John V. Heymach;Jia Wu;Xiuning Le - 通讯作者:
Xiuning Le
PP01.42 EGFR Germline Mutations in Lung Adenocarcinoma: A Single-Center Experience
PP01.42 肺腺癌中的表皮生长因子受体胚系突变:单中心经验
- DOI:
10.1016/j.jtho.2024.05.283 - 发表时间:
2024-07-01 - 期刊:
- 影响因子:20.800
- 作者:
Kelsey Pan;Jennifer Owens;Charles Lu;Edward Ostrin;Mark Routbort;Jianjun Zhang;John V. Heymach;Xiuning Le - 通讯作者:
Xiuning Le
Poziotinib in Treatment-Naive NSCLC Harboring emHER2/em Exon 20 Mutations: ZENITH20-4, A Multicenter, Multicohort, Open-Label, Phase 2 Trial (Cohort 4)
波齐替尼治疗初治携带 emHER2/em 外显子 20 突变的非小细胞肺癌:ZENITH20-4,一项多中心、多队列、开放标签、2 期试验(队列 4)
- DOI:
10.1016/j.jtho.2023.03.016 - 发表时间:
2023-08-01 - 期刊:
- 影响因子:20.800
- 作者:
Robin Cornelissen;Arsela Prelaj;Sophie Sun;Christina Baik;Mirjana Wollner;Eric B. Haura;Hirva Mamdani;Jonathan W. Riess;Federico Cappuzzo;Marina C. Garassino;John V. Heymach;Mark A. Socinski;Szu-Yun Leu;Gajanan Bhat;Francois Lebel;Xiuning Le;ZENITH20-4 Investigators - 通讯作者:
ZENITH20-4 Investigators
John V. Heymach的其他文献
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{{ truncateString('John V. Heymach', 18)}}的其他基金
Molecular features impacting drug resistance in atypical EGFR exon 18 and exon 20 mutant non-small cell lung cancers and the development of novel mutant-selective inhibitors
影响非典型 EGFR 外显子 18 和外显子 20 突变非小细胞肺癌耐药性的分子特征以及新型突变选择性抑制剂的开发
- 批准号:
10377501 - 财政年份:2020
- 资助金额:
$ 29.05万 - 项目类别:
Molecular features impacting drug resistance in atypical EGFR exon 18 and exon 20 mutant non-small cell lung cancers and the development of novel mutant-selective inhibitors
影响非典型 EGFR 外显子 18 和外显子 20 突变非小细胞肺癌耐药性的分子特征以及新型突变选择性抑制剂的开发
- 批准号:
10593969 - 财政年份:2020
- 资助金额:
$ 29.05万 - 项目类别:
Therapeutic strategies against EGFR exon 20 mutant lung cancer
EGFR外显子20突变肺癌的治疗策略
- 批准号:
10530622 - 财政年份:2019
- 资助金额:
$ 29.05万 - 项目类别:
Therapeutic strategies against EGFR exon 20 mutant lung cancer
EGFR外显子20突变肺癌的治疗策略
- 批准号:
10062900 - 财政年份:2019
- 资助金额:
$ 29.05万 - 项目类别:
Therapeutic strategies against EGFR exon 20 mutant lung cancer
EGFR外显子20突变肺癌的治疗策略
- 批准号:
10304886 - 财政年份:2019
- 资助金额:
$ 29.05万 - 项目类别:
Therapeutic strategies against EGFR exon 20 mutant lung cancer
EGFR外显子20突变肺癌的治疗策略
- 批准号:
9885320 - 财政年份:2019
- 资助金额:
$ 29.05万 - 项目类别:
Therapeutic approaches for LKB1-deficient non-small cell lung cancer
LKB1缺陷型非小细胞肺癌的治疗方法
- 批准号:
9890784 - 财政年份:2016
- 资助金额:
$ 29.05万 - 项目类别:
Markers and therapeutic strategies for overcoming chemoradiotherapy resistance
克服放化疗耐药性的标志物和治疗策略
- 批准号:
8703513 - 财政年份:2011
- 资助金额:
$ 29.05万 - 项目类别:
Markers and therapeutic strategies for overcoming chemoradiotherapy resistance
克服放化疗耐药性的标志物和治疗策略
- 批准号:
8509639 - 财政年份:2011
- 资助金额:
$ 29.05万 - 项目类别:
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