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EFFECT OF VITAMIN D3 ON THE IFNA SIGNATURE IN PATIENTS WITH LUPUS

EFFECT OF VITAMIN D3 ON THE IFNA SIGNATURE IN PATIENTS WITH LUPUS
维生素 D3 对狼疮患者 IFNA 特征的影响
批准号：
8167262
负责人：
Cynthia Aranow
金额：
$1.02万
依托单位：
FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-04-01 至 2011-03-31
来源：
https://reporter.nih.gov/project-details/8167262
关键词：
CholecalciferolComputer Retrieval of Information on Scientific Projects DatabaseFundingGrantInstitutionInterferonsLupusMonitorPatientsRandomizedResearchResearch PersonnelResourcesSafetySourceSupplementationUnited States National Institutes of HealthVitamin Dclinical effectdouble-blind placebo controlled trialspelling

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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This multi-center double-blind placebo controlled trial will investigate the effect of vitamin D supplementation on the interferon signature in patients with systemic lupus erythrematosus. Vitamin D deficient patients with spell out who possess the interferon signature will be randomized to receive 0, 2000 or 4000 IU/daily of cholecalciferol (vitamin D3) for 12 weeks. Potential clinical effects as well as safety will be assessed and monitored
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