The Insight Toolkit, Version 4 (Carnegie-Mellon)

1999年，NLM高性能计算和通信办公室授予多个合同，组建一个软件开发联盟，创建和开发应用程序编程接口（API），并首次实现分段和注册工具包，随后被命名为Insight工具包（ITK）。最初的合同包括6家承包商：GE全球研究公司、insights公司、Kitware公司、北卡罗来纳大学教堂山分校、宾夕法尼亚大学和田纳西大学。这六家承包商与五个分包商合作：哈佛大学医学院、宾夕法尼亚大学、匹兹堡大学、哥伦比亚大学和犹他大学。最初的ITK奖的演出期从1999年开始，到2003年结束。由此产生的系统最初是为了计算机辅助探索国家医学图书馆（NLM）可见人类（VHP）数据集。这个小组的最终成果是一个专注于分割和配准算法的开源软件库，直接插入到公共领域，现在帮助支持全球范围内的图像分析和其他领域的研究。像ITK这样的开源计划通过提供进行高级调查所必需的软件基础设施的基础，帮助降低进入复杂研究领域的门槛。修改ITK被认为是通过软件对国家基础设施的贡献。对该软件的培养和维护进行了仔细的考虑，向开发人员保证，该软件将继续得到新版本、错误修复和持续增长的支持。Insight Toolkit （ITK）于2009年9月发布了ITK 3.16版本（参见URL: http://www.itk.org）。尽管通过系统技术合同继续提供支持，NLM希望此时重新审视ITK的底层设计和软件体系结构。ITK的初始设计会议在1999年11月初举行，而该软件的设计决策是针对2004年预期的技术，这些决定现在显示出它们的年龄。

In 1999, the NLM Office of High Performance Computing and Communications awarded multiple contracts for the formation of a software development consortium to create and develop an application programmer interface (API) and first implementation of a segmentation and registration toolkit, subsequently named the Insight Toolkit (ITK). The original awards included six contractors: GE Global Research, Insightful, Inc., Kitware, Inc., the University of North Carolina at Chapel Hill, the University of Pennsylvania, and the University of Tennessee. The six contractors were partnered with five subcontractors: Harvard University Medical School, the University of Pennsylvania, the University of Pittsburgh, Columbia University, and the University of Utah. The period of performance for the original ITK awards began in 1999 and ended in 2003. The resulting system was originally intended for computer-assisted exploration of the National Library of Medicine (NLM) Visible Human (VHP) data sets. The final deliverable for this group was an open-source software library concentrating on segmentation and registration algorithms, directly inserted into the public domain that now helps support research worldwide in image analysis and in other domains. Open-source initiatives such as ITK help to lower the barriers to entry in complex research fields by providing the foundations of the software infrastructure necessary to conduct advanced investigations. Revising ITK is considered a contribution to the nation's infrastructure through software. Careful thought has been placed on the cultivation and maintenance of this software, assuring developers that the software will remain supported with new releases, bug fixes, and continuing growth. The Insight Toolkit (ITK) is currently available with the release, ITK version 3.16, announced in September 2009 (see the URL: http://www.itk.org). Despite continued support through systems technology contracts, NLM wishes to revisit the underlying design and software architecture for ITK at this time. The initial design meeting for ITK was held in early November 1999, and while the design decisions for this software were targeted for the anticipated technology of 2004, those decisions are now showing their age.