Detroit Reproductive Career Development Research Center

描述（由申请人提供）：拟议的职业发展计划的总体目标是在与妇女生殖健康相关的基础，翻译和/或临床领域发展独立的OB/GYN医生研究人员。韦恩州立大学（WSU）对这样做的机构承诺在历史上是强大的，这导致了强大的研究和培训环境，包括75，000平方英尺的C.S. Mott人类生长与发育中心和NIH围产期学研究分支。WSU是一个少数民族服务机构（非洲裔和阿拉伯裔美国人）。妇女生殖健康研究学者将根据咨询委员会的建议，从表现出对研究感兴趣和有研究经验的候选人（地方和国家）中任命。将与梅哈里医学院和圣胡安的波多黎各大学建立积极的伙伴关系，招聘代表性不足群体的成员。根据前两个支助期间取得的经验，挑选标准更加明确。学者的培训将根据他们过去的经验和能力进行个性化。任何时候都将招收三名个人，预计总共将培训六名学者。拟议的主要研究者和研究总监在研究、培训和管理方面经验丰富。导师将是经验丰富的调查员，他们有培训记录，有与妇女生殖健康广泛相关的研究方案。这些研究人员将得到广泛的当代，先进的临床和研究资源的补充。将有六个培训目标：1）提供个性化的课程/讲座/研讨会; 2）提供必要的辅助技能和支持资源，以满足每个学者的独特需求; 3）提供与每个学者的长期研究兴趣相关的关键，指导的研究经验; 4）教每个学者写一个有竞争力的补助金申请; 5）积极主动地与杰出的，学科相关的高级研究人员建立联系;以及6）确保每位学者在负责任的研究行为中有良好的基础。由外部评估员对该计划进行的年度评估将包括对过程和结果的客观分析。咨询委员会成员将进行监督，并评估方案的有效性。学者将完成他们的培训时，他们已经证明达到了研究的独立性，客观地衡量等标准的能力，成功地竞争独立的赠款支持。学者将在离开该计划后进行跟踪。总的来说，预计培训将大大有助于提高国家今后进行妇女健康研究的能力。 公众相关性：拟议的培训与公共卫生有关，因为妇产科医生职业发展的机会和支持对于降低妇女整个生命周期的发病率和死亡率至关重要。韦恩州立大学提供了独特的基础设施，资源和导师，这将使其成为下一代临床和转化研究人员的强大贡献者，为妇女的生殖健康，从而为我们所服务的多元化，城市女性人口的积极临床成果。

DESCRIPTION (provided by applicant): The overall objective of the proposed career development program is to develop independent OB/GYN physician-researchers in basic, translational and/or clinical areas related to women's reproductive health. Institutional commitment to doing so is historically strong at Wayne State University (WSU), which has resulted in a strong research and training environment that includes the 75,000 sq ft C.S. Mott Center for Human Growth & Development and NIH's Perinatology Research Branch. WSU is a minority-serving institution (African & Arab Americans). Women's Reproductive Health Research Scholars will be appointed, based on recommendations of an Advisory Committee, from a pool of candidates (local and national) who have demonstrated interest and prior experience in research. Members of underrepresented groups will be recruited in proactive partnerships with Meharry Medical College and the Univ. of Puerto Rico in San Juan. Selection criteria have been sharpened by experience gained during the previous two periods of support. Training of Scholars will be individualized based on their past experiences and competences. Three individuals will be enrolled at any one time, with the expectation that a total of six Scholars will be trained. The proposed PI and Research Director are well experienced in research, training and administration. Mentors will be experienced investigators with training track records who have research programs that are broadly relevant to women's reproductive health. These investigators will be complemented by a wide range of contemporary, sophisticated clinical and research resources. There will be six training aims: 1) Provide individualized coursework / lectures / seminars; 2) Provide essential ancillary skills and support resources to meet unique needs of each Scholar; 3) Provide a critical, mentored research experience that is relevant to each Scholar's long-term research interest; 4) Teach each Scholar to write a competitive grant application; 5) Proactively network each Scholar with prominent, disciplinarily relevant senior investigators; and 6) Assure that each Scholar is well grounded in the responsible conduct of research. Annual evaluation of the program by an outside evaluator will include objective analysis of both process and outcome. Advisory Committee members will provide oversight and also assess programmatic effectiveness. Scholars will complete their training when they have demonstrably reached research independence, objectively measured by such criteria as ability to compete successfully for independent grant support. Scholars will be tracked after leaving the program. Overall, the training is expected to contribute substantively to the nation's capacity for future conduct of women's health research. PUBLIC RELEVANCE: The proposed training is relevant to public health because opportunities for, and support of, career development of Obstetrician Gynecologists is essential for reduction of morbidity and mortality of women throughout their life cycle. Wayne State University provides unique infrastructure, resources, and mentors that will make it a strong contributor to the next generation of clinical and translational researchers for women's reproductive health and, thereby, to the positive clinical outcomes of the diverse, urban female population we serve.