The Role of PARP-1 in Hormone-Regulated Transcription
The Role of PARP-1 in Hormone-Regulated Transcription
批准号:
8225315
负责人:
WILLIAM Lee KRAUS
金额:
$31.61万
依托单位国家:
美国
项目类别:
财政年份:
2004
资助国家:
美国
项目状态:
已结题
起止时间:
2004-09-30 至 2013-05-31
关键词:
AddressAdenosine Diphosphate RiboseAffectAnabolismArchitectureAreaBindingBinding ProteinsBiochemicalBiological AssayBreast Cancer TreatmentCell NucleusCellsChromatinChromatin Remodeling FactorChromatin StructureDNA BindingDiseaseEP300 geneEnvironmentEnzymesEstrogen Receptor 1Estrogen Receptor ModulatorsEstrogen Receptor alphaEstrogen ReceptorsEstrogensFamilyGene ExpressionGene Expression RegulationGene TargetingGenesGenetic TranscriptionGenomeHistone AcetylationHistone H1Histone H1(s)HistonesHormonesIn VitroLeadLigandsMediatingMessenger RNAMetabolismMolecularNicotinamide adenine dinucleotideNuclearNuclear ReceptorsNucleosomesOutcomeOutputPatternPlayPoly(ADP-ribose) PolymerasesProteinsRNA Polymerase IIRegulationRegulator GenesRoleSeriesSignal TransductionStructureTestingTo specifyTranscriptional RegulationVariantbasechromatin remodelinghistone modificationhuman NCYM proteinhuman diseasein vitro Assayin vivoinsightmalignant breast neoplasmmemberpolymerizationpromoterpublic health relevanceresearch studytherapeutic target
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