Conformational duality in the human chemokine Ltn/XCL1
Conformational duality in the human chemokine Ltn/XCL1
批准号:
8301087
负责人:
Brian F Volkman
金额:
$35.17万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-08-01 至 2013-06-30
关键词:
AdoptedAffinityAmino Acid SequenceAmino AcidsApoptosisAutoimmune DiseasesBehaviorBindingBiologicalC-terminalCD4 Positive T LymphocytesCell surfaceChemotactic FactorsChronicCodeDNA Sequence RearrangementDevelopmentDiagnosticDiseaseDissectionDisulfidesDockingElementsEmbryonic DevelopmentEpitopesEquilibriumExcisionExtracellular MatrixFamilyFluorescenceFree EnergyFundingG Protein-Coupled Receptor GenesG-Protein-Coupled ReceptorsGlycosaminoglycansGoalsGrantHIV InfectionsHomingHumanImmobilizationImmune responseIndividualInfectionInflammationIonic StrengthsKineticsLigandsLinkLymphocyteMapsMeasurementMeasuresMediatingMolecular ConformationMultiple SclerosisMutationNatureNeoplasm MetastasisPathway interactionsPatternPeptide Sequence DeterminationPhysiologicalPopulationProcessPropertyProteinsReactionReceptor ActivationRecruitment ActivityRelaxationResearchRheumatoid ArthritisScreening procedureSiteSolutionsStem cellsStructureSurfaceTemperatureTestingTherapeutic AgentsThermodynamicsTuberculosisVertebral columnXCL1 geneXCR1 geneabstractingbasecell motilitychemokinechemokine receptorcrosslinkflexibilityglobular proteinin vivoinhibitor/antagonistinsightmembermutantnovelpolypeptidepreventprotein foldingreceptorresearch studyresponse to injurysimulationsmall moleculetyrosine O-sulfatevirtual
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会议论文
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批准号:8245006
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批准号:8312146
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资助金额:$8.5万
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Sulfotyrosine-guided discovery of small molecule chemokine inhibitors
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批准号:9892823
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财政年份:2009
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依托单位:
Conformational duality in the human chemokine Ltn/XCL1
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批准号:7846710
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财政年份:2009
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Structural basis for selctive lysis of anthrax and drug-resistant S. aureus
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财政年份:2009
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财政年份:2005
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依托单位:
Conformational duality in the human chemokine Ltn/XCL1
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批准号:7407385
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财政年份:2005
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依托单位:
Conformational duality in the human chemokine Ltn/XCL1
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批准号:7587463
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Conformational duality in the human chemokine Ltn/XCL1
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Conformational duality in the human chemokine Ltn/XCL1
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批准号:6861168
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Structural Basis for Chemokine Function
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依托单位:
海外基金