Tcf3 function in spinal progenitor maintenance

Tcf3 在脊髓祖细胞维持中的功能

• 批准号: 8270432
• 负责人: RICHARD I DORSKY
• 金额: $ 37.38万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8270432
• 关键词: Adult; Biochemistry; Biological Assay; Brain Diseases; Candidate Disease Gene; Cell division; Cells; Characteristics; DNA Methylation; Data Set; Development; Disease; Down-Regulation; Embryo; Epithelial; Fishes; Future; Gene Expression; Gene Targeting; Genes; Genetic; Genetic Epistasis; Goals; In Situ Hybridization; Individual; Injury; Laboratories; Lead; Maintenance; Mediating; Messenger RNA; Methyltransferase; Microarray Analysis; Modeling; Molecular; Molecular Genetics; Multipotent Stem Cells; Nervous System Trauma; Neuraxis; Neuroglia; Neurons; Pathway interactions; Play; Population; Process; Proteins; Public Health; Quality of life; Research Proposals; Role; Signal Transduction; Spinal; Spinal Cord; Stem cells; Study models; Testing; Time; Tissues; Work; Zebrafish; injury and repair; loss of function; mutant; nerve stem cell; nervous system development; nervous system disorder; neurogenesis; novel; overexpression; pluripotency; progenitor; repaired; research study; self-renewal; tissue regeneration

项目成果

Radial glial progenitors repair the zebrafish spinal cord following transection.

• DOI: 10.1016/j.expneurol.2014.03.017
• 发表时间: 2014-06
• 期刊: EXPERIMENTAL NEUROLOGY
• 影响因子: 5.3
• 作者: Briona, Lisa K.;Dorsky, Richard I.
• 通讯作者: Dorsky, Richard I.

Wnt/ß-catenin signaling is required for radial glial neurogenesis following spinal cord injury.

• DOI: 10.1016/j.ydbio.2015.03.025
• 发表时间: 2015-07-01
• 期刊: DEVELOPMENTAL BIOLOGY
• 影响因子: 2.7
• 作者: Briona, Lisa K.;Poulain, Fabienne E.;Mosimann, Christian;Dorsky, Richard I.
• 通讯作者: Dorsky, Richard I.