Targeting the Hedgehog pathway in glioma tumor-initiating cells

靶向神经胶质瘤肿瘤起始细胞中的 Hedgehog 通路

• 批准号: 8195841
• 负责人: MICHAEL KANE COOPER
• 金额: --
• 依托单位: VETERANS HEALTH ADMINISTRATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8195841
• 关键词: Adjuvant Chemotherapy; Behavior; Biological; Biological Assay; Brain Neoplasms; Cell Proliferation; Cell Survival; Cells; Clinical; Collection; Data; Diagnosis; Disease; Erinaceidae; Excision; Foundations; GLI gene; Gene Targeting; Glioblastoma; Glioma; Goals; Growth; Hematologic Neoplasms; Human; Immunodeficient Mouse; Immunophenotyping; Individual; Infiltrative Growth; Investigation; Ligands; Malignant Glioma; Malignant Neoplasms; Measures; Modeling; Molecular; Molecular Target; Mus; Nature; Oligodendroglioma-Astrocytoma; Operative Surgical Procedures; PTCH gene; Pathway interactions; Patients; Phenotype; Pre-Clinical Model; Primary Brain Neoplasms; Primary Neoplasm; Radiation; Radiation therapy; Recurrence; Regulation; Research; Resistance; Sampling; Signal Transduction; Specimen; Surveys; Testing; Therapeutic; Therapeutic Intervention; Transplantation; United States; Veterans; Work; World Health Organization; Xenograft Model; Xenograft procedure; base; cancer stem cell; cell growth; cell type; chemotherapy; design; in vivo; innovation; mouse model; novel; outcome forecast; response; smoothened signaling pathway; statistics; tumor; tumor growth