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Targeting Renal Purinergic Signaling for the Treatment of Lithium-induced NDI

Targeting Renal Purinergic Signaling for the Treatment of Lithium-induced NDI
靶向肾脏嘌呤信号传导治疗锂诱导的 NDI
批准号：
8195888
负责人：
BELLAMKONDA K KISHORE
金额：
$0.0万
依托单位：
VA SALT LAKE CITY HEALTHCARE SYSTEM
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-04-01 至 2014-03-31
来源：
https://reporter.nih.gov/project-details/8195888
关键词：
AcuteAdverse effectsAffectAgonistAmilorideAnxietyArgipressinBiologicalBiological ModelsBipolar DisorderBloodCardiovascular systemCell Culture TechniquesCellsChemosensitizationChronicClinicalClinical TrialsCoagulation ProcessCombined Modality TherapyConsciousCulture MediaDataDehydrationDevelopmentDrug Delivery SystemsDuct (organ) structureElderlyElectrolytesEquilibriumEvaluationEventFormulariesFreedomFunctional disorderFundingFutureGeneral PopulationGeneticGoalsHealthcareHypernatremiaHypovolemiaInfusion proceduresInjection of therapeutic agentInterventionIntoxicationInvestigationIraqKidneyKnock-outKnockout MiceKnowledgeLaboratoriesLifeLiquid substanceLithiumMajor Depressive DisorderMarinesMarketingMediatingMental DepressionMethodsMissionModalityModelingMolecularMorbidity - disease rateMusNatureNephrogenic Diabetes InsipidusNucleotidesOutcomeP2Y2 receptorPTGS2 genePathway interactionsPatientsPharmaceutical PreparationsPhysiologicalPlavixPlayPost-Traumatic Stress DisordersPrevalencePurinoceptorRattusReceptor GeneReplacement TherapyReportingResearchResistanceRiskRoleSafetyScreening procedureSignal TransductionSoldierStagingSubstance abuse problemSurveysSystemTechniquesTherapeuticTherapeutic AgentsTherapeutic UsesTissue SampleTissuesUrineV2 ReceptorsVasopressinsVeteransVietnamWarWaterWild Type MouseWorkabstractinganalogbaseclinical practiceclinically relevantclopidogreldesignextracellularfeedinghemodynamicshigh riskimprovedin vivoinfancyinhibitor/antagonistinnovationinsightmeetingsmortalitynovelolder patientoperationpreventpurinoceptor P2Y4receptorresearch studyresponsesocialsuccesssuicidal riskurinary

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Targeting Renal Purinergic Signaling for the Treatment of Lithium-induced NDI
Targeting Renal Purinergic Signaling for the Treatment of Lithium-induced NDI
Targeting Renal Purinergic Signaling for the Treatment of Lithium-induced NDI
Targeting Renal Purinergic Signaling for the Treatment of Lithium-induced NDI
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