Glutamate dyshomeostasis: The role of glutamate transport dysfunction in Alzheim

谷氨酸稳态失调：谷氨酸转运功能障碍在阿尔茨海默病中的作用

• 批准号: 7907841
• 负责人: David G Cook
• 金额: --
• 依托单位: VA PUGET SOUND HEALTHCARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7907841
• 关键词: APP-PS1; Accounting; Address; Affect; Aging; Alleles; Alzheimer' s Disease; Amyloid beta-Protein Precursor; Animal Model; Astrocytes; Biological; Brain; Brain region; Clinical; Clinical Trials; Cognition; Cognitive; Data; Disease; Disease Progression; Family; Functional disorder; Glutamate Transporter; Glutamates; Hippocampus (Brain); Human; Light; Memantine; Memory; Modeling; Mus; Neurobehavioral Manifestations; Neuronal Plasticity; Neurotransmitters; Pathogenesis; Pathology; Patients; Pharmaceutical Preparations; Play; Population; Post-Translational Protein Processing; Presynaptic Terminals; Process; Property; Relative (related person); Risk; Risk Factors; Role; Staging; Synapses; System; Testing; Therapeutic; Veterans; adduct; brain cell; clinically relevant; excitotoxicity; familial Alzheimer disease; human tissue; mouse model; mutant; neurotransmission; new therapeutic target; novel; presenilin-1; prevent; public health relevance; tool; treatment strategy